Age-associated difference in circadian sleep-wake and rest-activity rhythms
Age-associated difference in circadian sleep-wake and rest-activity rhythms
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DOI：
10.1016/s0031-9384(02)00733-3
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发表时间：
2002-08-01
影响因子：
2.9
通讯作者：
Zhou, JN
中科院分区：
文献类型：
--
作者：
Huang, YL;Liu, RY;Zhou, JN
采用腕关节活动监测仪，我们调查了65名青年、中年、老年和老年受试者在自然环境条件下的睡眠和休息-活动模式。为了评估年龄和性别对睡眠和活动昼夜节律的影响，进行了多变量分析。年龄显著影响昼夜睡眠和休息活动节律。在老年组和高龄组中，活动记录仪对“实际睡眠时间”和“睡眠效率”的估计值显著下降。老年组和高龄组的“睡眠潜伏期”、“夜间觉醒”次数、睡眠碎片和白天小睡的估计值显著增加。关于休息和活动的昼夜节律模式，日间稳定性（IS）在四个年龄组中是相似的，而老年人和年龄最大的受试者表现出显着增加的日内变异性（IV）和夜间活动和振幅（AMP）下降。目前的研究表明，在衰老过程中，昼夜睡眠和休息活动节律减弱和破碎。然而，没有发现与性别有关的差异。（C）2002年爱思唯尔科学公司。All rights reserved.
Using actigraphic monitoring of wrist activity, we investigated the sleep and rest-activity patterns of 65 young, middle-aged, old and the oldest subjects in their natural environmental conditions. To assess the effects of age and gender on sleep and circadian rhythms in activity, multivariate analyses were performed. Age significantly affected circadian sleep and rest-activity rhythms. In the old and oldest groups, the actigraphic estimates of "actual sleep time" and "sleep efficiency" decreased significantly. The estimates of "sleep latency," the number of "nighttime awakening," sleep fragmentation and daytime naps significantly increased in the old and oldest groups. Concerning the circadian patterning of rest and activity, the interdaily stability (IS) was similar in the four age groups, while the old and oldest subjects showed significant increases in intradaily variability (IV) and nighttime activity and a decrease in amplitude (AMP). The present study demonstrated weakened and fragmented circadian sleep and rest-activity rhythms during aging. However, no gender-related difference was found. (C) 2002 Elsevier Science Inc. All rights reserved.