A strategy for the synthesis of 2,3-disubstituted indoles starting from N-(o-halophenyl)allenamides
A strategy for the synthesis of 2,3-disubstituted indoles starting from N-(o-halophenyl)allenamides
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DOI：
10.1039/b707338k
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发表时间：
2007-01-01
影响因子：
3.2
通讯作者：
Sasaki, Makoto
中科院分区：
文献类型：
--
作者：
Fuwa, Haruhiko;Sasaki, Makoto
基于分子内碳钯化-阴离子捕获级联反应合成了2，3-二取代吲哚衍生物，其中吡咯环的构建和吲哚C2和C3位的功能化是通过广泛使用钯（0）催化的偶联反应实现的。
A strategy for the synthesis of 2,3-disubstituted indole derivatives based on an intramolecular carbopalladation-anion capture cascade has been developed, wherein construction of the pyrrole ring and functionalisation of the indole C2 and C3 positions were achieved by extensive use of palladium( 0)catalysed coupling reactions.