The Arizona Cognitive Test Battery for Down Syndrome: Test-Retest Reliability and Practice Effects
The Arizona Cognitive Test Battery for Down Syndrome: Test-Retest Reliability and Practice Effects
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DOI：
10.1352/1944-7558-122.3.215
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发表时间：
2017-05-01
影响因子：
2.1
通讯作者：
Sherman, Stephanie
中科院分区：
文献类型：
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作者：
Edgin, Jamie O.;Anand, Payal;Sherman, Stephanie
一项多中心研究调查了一组评估唐氏综合征（DS）患者神经认知功能的重测信度和实践效果。本研究旨在确定这些指标作为临床试验潜在终点的适当性。神经认知任务和家长报告的措施，包括亚利桑那州认知测试电池（ACTB）进行了管理，以54名年轻的参与者DS（7-20岁）与轻度至中度水平的智力残疾的初始基线评估和3个月后的后续评估。虽然ACTB措施的修订表明，结果表明足够的可靠性和抗实践效果的一些措施。ACTB为记忆、运动规划、行为调节和注意力的重复测试提供了可行的选择。执行功能的替代措施是必要的。
A multisite study investigated the test-retest reliability and practice effects of a battery of assessments to measure neurocognitive function in individuals with Down syndrome (DS). The study aimed to establish the appropriateness of these measures as potential endpoints for clinical trials. Neurocognitive tasks and parent report measures comprising the Arizona Cognitive Test Battery (ACTB) were administered to 54 young participants with DS (7-20 years of age) with mild to moderate levels of intellectual disability in an initial baseline evaluation and a follow-up assessment 3 months later. Although revisions to ACTB measures are indicated, results demonstrate adequate levels of reliability and resistance to practice effects for some measures. The ACTB offers viable options for repeated testing of memory, motor planning, behavioral regulation, and attention. Alternative measures of executive functioning are required.