Wheel running decreases palatable diet preference in Sprague-Dawley rats.
Wheel running decreases palatable diet preference in Sprague-Dawley rats.
复制标题
DOI：
10.1016/j.physbeh.2015.03.019
复制
发表时间：
2015-10-15
影响因子：
2.9
通讯作者：
Liang NC
中科院分区：
文献类型：
--
作者：
Moody L;Liang J;Choi PP;Moran TH;Liang NC
体育活动不仅对改善某些疾病状况，而且对预防多种疾病的发展有有益的作用。本研究以雄性和雌性大鼠为实验对象，研究了滚轮跑对鼠粮和高脂、高糖饮食摄入的影响。实验1表明，急性轮跑导致雄性大鼠对HF或HS饮食的强烈回避。虽然雌性大鼠最初表现出完全回避两种美味的饮食，但回避HS饮食是短暂的。实验2表明，无论饮食顺序和轮跑通道呈现方式如何，雄性大鼠的HF饮食偏好都有所下降。另一方面，女性HF饮食偏好的跑步相关变化取决于测试计划。在雌性大鼠中，同时提供HF饮食和跑步会导致短暂的完全HF饮食避免，而在HF饮食之前的跑步经历不会影响对HF饮食的高度偏好。雌性卵巢切除术导致的HF饮食偏好模式与同时暴露于HF和轮式跑步通道时的雄性大鼠相似，但与在HF暴露之前跑步的完整雌性大鼠相似。总的来说，结果表明，轮转与美味饮食偏好的变化有关，这在一定程度上取决于性别。此外，卵巢激素在某些性别差异中起作用。这些数据揭示了运动相关的美味饮食偏好变化背后的复杂机制。
Physical activity has beneficial effects on not only improving some disease conditions but also by preventing the development of multiple disorders. Experiments in this study examined the effects of wheel running on intakes of chow and palatable diet e.g. high fat (HF) or high sucrose (HS) diet in male and female Sprague Dawley rats. Experiment 1 demonstrated that acute wheel running results in robust HF or HS diet avoidance in male rats. Although female rats with running wheel access initially showed complete avoidance of the two palatable diets, the avoidance of the HS diet was transient. Experiment 2 demonstrated that male rats developed decreased HF diet preferences regardless of the order of diet and wheel running access presentation. Running associated changes in HF diet preference in females, on the other hand, depended on the testing schedule. In female rats, simultaneous presentation of the HF diet and running access resulted in transient complete HF diet avoidance whereas running experience prior to HF diet access did not affect the high preference for the HF diet. Ovariectomy in females resulted in HF diet preference patterns that were similar to those in male rats during simultaneous exposure of HF and wheel running access but similar to intact females when running occurred before HF exposure. Overall, the results demonstrated wheel running associated changes in palatable diet preferences that were in part sex dependent. Furthermore, ovarian hormones play a role in some of the sex differences. These data reveal complexity in the mechanisms underlying exercise associated changes in palatable diet preference.