Adverse effects of valproate on bone: Defining a model to investigate the pathophysiology

Adverse effects of valproate on bone: Defining a model to investigate the pathophysiology
复制标题

DOI：
10.1111/j.1528-1167.2009.02516.x
复制
发表时间：
2010-06
期刊：
Epilepsia
影响因子：
5.6
通讯作者：
S. Senn;S. Kantor;Ingrid J. Poulton;M. Morris;N. Sims;T. O’Brien;J. Wark
S. Senn;S. Kantor;Ingrid J. Poulton;M. Morris;N. Sims;T. O’Brien;J. Wark
中科院分区：
医学1区
文献类型：
--
作者：
S. Senn;S. Kantor;Ingrid J. Poulton;M. Morris;N. Sims;T. O’Brien;J. Wark

文献摘要

被引文献

相似文献

目的：骨疾病和骨折是常见的慢性抗癫痫药物（AED）治疗，但其潜在的机制知之甚少。本研究旨在表征丙戊酸盐的不良骨效应，并确定对这些效应耐药或敏感的小鼠品系。
Purpose: Bone disease and fractures are common with chronic antiepileptic drug (AED) therapy, but the underlying mechanisms are poorly understood. This study aimed to characterize adverse bone effects of valproate and to identify mouse strains either resistant or sensitive to these effects.