Current perception threshold evaluation of the female urethra
Current perception threshold evaluation of the female urethra
复制标题
女性尿道电流知觉阈值评估
DOI：
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发表时间：
2003
影响因子：
1.8
通讯作者：
J. T. Benson
中科院分区：
文献类型：
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作者：
K. Kenton;K. Kenton;E. Fuller;J. T. Benson
本研究的目的是确定当前知觉阈值(CPT)在女性尿路评估中的可行性。没有LUT功能障碍的女性接受了CPT测试，使用连接到尿路环形电极的神经计(Neurotron，Inc.，巴尔的摩，马里兰州)。测试以标准化的方式在三个频率(2000、250和5赫兹)下进行，以确定受试者第一次感觉到刺激的时间以及感觉到的刺激何时变得痛苦。所有10名受试者都完成了当前知觉阈值测试。受试者第一次感受到刺激的水平显著低于刺激变得痛苦时的水平(P<；0.002)。2 0 0 0年、2 5 0和5 0 0赫兹的平均感觉阈值分别为70μA(14~2 30)、2 5μA(4~80)和17μA(2~78)，平均痛阈值分别为2 2 9μA(5 4~42 4)、91μA(2 4~162)和110μA(25~2 0 0)。受试者在250赫兹和5赫兹时的知觉阈值没有差异(P=0.206)。知觉阈值和痛阈值在所有其他频率上都有显著不同。没有LUT功能障碍的女性的知觉阈值低于痛觉阈值，并且能够以不同的频率区分大多数刺激。目前对女性尿路的知觉阈值测试在技术上是可行的，并可能有助于评估不同传入通路的功能完整性。
The purpose of this study was to determine the feasibility of the current perception threshold (CPT) evaluation in the female urethra. Women without LUT dysfunction underwent CPT testing using a Neurometer (Neurotron, Inc., Baltimore, MD) connected to a ring electrode in the urethra. Testing was done in a standardized fashion at three frequencies, 2000, 250 and 5 Hz, to determine when subjects first perceived the stimuli and when perceived stimuli became painful. Current perception threshold testing was accomplished in all 10 subjects studied. The level at which subjects first perceived stimuli was significantly lower than that at which the stimuli became painful (P<0.002). Mean perception thresholds at 2000, 250 and 5 Hz were 70 μA (range 14–230), 25 μA (4–80) and 17 μA (2–78), respectively, and mean pain thresholds were 229 μA (54–424), 91 μA (24–162) and 110 μA (25–200), respectively. There was no difference in subjects' perception thresholds at 250 and 5 Hz (P=0.206). Perception thresholds and pain thresholds were significantly different at all other frequencies. Women without LUT dysfunction have lower perception thresholds than pain thresholds and can distinguish between most stimuli at different frequencies. Current perception threshold testing of the female urethra is technically feasible and may be useful for assessing the functional integrity of different afferent pathways.