Shooting for the moon: Genome editing for pig heart xenotransplantation.
Shooting for the moon: Genome editing for pig heart xenotransplantation.
复制标题
向月球射击：猪心脏异种移植的基因组编辑。
DOI：
10.1016/j.jtcvs.2022.04.032
复制
发表时间：
2023
期刊：
影响因子：
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通讯作者：
Pierson3rd,RichardN
中科院分区：
文献类型：
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作者：
Cooper,DavidKC;Raza,SSikandar;Chaban,Ryan;Pierson3rd,RichardN
除了这些方法之外，基因编辑还可用于解决猪器官与人类受体需求之间的任何生理不相容性。然而，迄今为止，猪的心脏功能在NHP似乎是令人满意的，虽然持续性心动过速是常见的。
DiscussionIn addition to these approaches, gene editing can be used to address any physiologic incompatibilities that are identified between the pig organ and the needs of the human recipient. To date, however, pig heart function in NHPs appears to be satisfactory, although a persistent tachycardia is common.