Methodology for identification of phenolic acids in complex phenolic mixtures by high-resolution two-dimensional nuclear magnetic resonance. Application to methanolic extracts of two oregano species
Methodology for identification of phenolic acids in complex phenolic mixtures by high-resolution two-dimensional nuclear magnetic resonance. Application to methanolic extracts of two oregano species
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DOI：
10.1021/jf9804591
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发表时间：
1998-10-01
影响因子：
6.1
通讯作者：
Boskou, A
中科院分区：
文献类型：
--
作者：
Gerothanassis, IP;Exarchou, V;Boskou, A
描述了分析天然产物中存在的几种酚类化合物的混合物的二维（2D）NMR光谱的光谱学方法。特别强调了标量耦合连接性的测定home 2D相关光谱（COSY），远程残基内连接性的完全相关光谱（TOCSY），和空间上接近，但不耦合的H-1核home 2D核奥弗豪泽效应光谱（NOESY/ROESY）。初步数据，以确定从两个牛至植物的甲醇提取物中的酚酸也有报道。
Spectroscopic methodology in analyzing two-dimensional (2D) NMR spectra of a mixture of several phenolic compounds that occur in natural products is described. Particular emphasis has been given to the determination of scalar coupling connectivities by homonuclear 2D correlated spectroscopy (COSY), remote intraresidue connectivities by totally correlated spectroscopy (TOCSY), and spatially close but uncoupled H-1 nuclei by homonuclear 2D nuclear Overhauser effect spectroscopy (NOESY/ROESY). Preliminary data to identify phenolic acids in the methanolic extracts from two oregano plants are also reported.