EVOLUTIONARY RELATIONSHIPS BETWEEN SUGAR KINASES AND TRANSCRIPTIONAL REPRESSORS IN BACTERIA
EVOLUTIONARY RELATIONSHIPS BETWEEN SUGAR KINASES AND TRANSCRIPTIONAL REPRESSORS IN BACTERIA
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DOI：
10.1099/13500872-140-9-2349
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发表时间：
1994-09-01
期刊：
影响因子：
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通讯作者：
SAIER, MH
中科院分区：
文献类型：
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作者：
TITGEMEYER, F;REIZER, J;SAIER, MH
我们鉴定了一个新的蛋白质家族(韩国家族)，它包括六个糖分解代谢操纵子的转录抑制因子，三个糖激酶和三个未知的开放阅读框架。对比对序列和系统发育树的分析可以预测这些蛋白质中保守结构域和残基的功能性质，以及导致该家族产生的进化分歧的途径。
We have characterized a new family of proteins (the ROK family) which includes six transcriptional repressors for sugar catabolic operons, three sugar kinases, and three unidentified open reading frames. Analyses of the aligned sequences and phylogenetic tree construction allow predictions regarding the functional nature of conserved domains and residues within these proteins as well as the pathway of evolutionary divergence that gave rise to the family.