Contribution of the immune system to follicle differentiation, ovulation and early corpus luteum formation

Contribution of the immune system to follicle differentiation, ovulation and early corpus luteum formation
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DOI:
10.21451/1984-3143-ar2019-0087
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发表时间:
2019-09-01
影响因子:
1.7
通讯作者:
Fair, Trudee
Fair, Trudee
中科院分区:
农林科学4区
文献类型:
--
作者:
Abdulrahman, Noof;Fair, Trudee

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免疫系统在牛排卵周卵泡分化、排卵和随后黄体形成中的作用,我们所知道的很大一部分来自于对几种哺乳动物家畜的研究结果。通过整合已发表的牛、羊和猪的组织学数据,并参考更全面的知识库,我们可以勾勒出免疫系统的关键细胞及其产生的细胞因子和生长因子,这些细胞因子和生长因子参与卵泡的分化和黄体化、排卵和早期卵泡发育。对这些贡献进行了回顾,并讨论了主要发现。
Much of what we know about the involvement of the immune system in periovulatory follicle differentiation, ovulation and subsequent formation of the corpus luteum in cattle is drawn from the findings of studies in several mammalian livestock species. By integrating published histological data from cattle, sheep and pigs and referring back to the more comprehensive knowledge bank that exists for mouse and humans we can sketch out the key cells of the immune system and the cytokines and growth factors that they produce that are involved in follicle differentiation and luteinization, ovulation and early follicle development. These contributions are reviewed and the key findings, discussed.