The Impact and Pathophysiologic Consequences of Coronary Artery Calcium Deposition in Percutaneous Coronary Interventions.
The Impact and Pathophysiologic Consequences of Coronary Artery Calcium Deposition in Percutaneous Coronary Interventions.
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经皮冠状动脉介入治疗中冠状动脉钙沉积的影响和病理生理后果。
DOI：
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
N. Shah
中科院分区：
文献类型：
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作者：
Michael S. Lee;N. Shah
冠状动脉钙的存在是晚期冠状动脉疾病的指示，是包括中风、心肌梗死和心脏骤停在内的临床事件的预测因子。认识与冠状动脉钙化相关的危险因素和临床意义对于确定预防措施和治疗方案至关重要。非侵入性和侵入性策略可以帮助量化这些钙化病变，并帮助患者选择可能使用的动脉粥样硬化消融设备。虽然轻度至中度钙化病变可以通过球囊血管成形术进行预扩张，但严重钙化的血管可能无法进行充分的预扩张，从而阻碍支架植入和最佳扩张，潜在地增加了早期和晚期并发症的风险。对于这些复杂病变，使用动脉粥样硬化切除术是一种非常宝贵的治疗选择，因为它能够改变斑块，改变严重钙化血管的顺应性，提高手术成功率。
The presence of coronary artery calcium is indicative of advanced coronary artery disease and is a predictor of clinical events including stroke, myocardial infarction, and cardiac arrest. Recognition of the risk factors and the clinical implications associated with coronary artery calcium is vital in identifying both preventative measures as well as treatment options. Non-invasive and invasive strategies can help quantify these calcified lesions and aid in appropriate patient selection for possible use of atheroablative devices. While mild to moderately calcified lesions can be predilated with balloon angioplasty, severely calcified vessels may be resistant to adequate predilatation and preclude stent delivery and optimal expansion, potentially increasing the risk of early and late complications. The use of atherectomy devices is an invaluable treatment option for these complex lesions, given the ability for plaque modification and changing the compliance of heavily calcified vessels, increasing procedural success rates.