HEMODYNAMIC CORRELATES OF ARTERIAL COMPLIANCE
HEMODYNAMIC CORRELATES OF ARTERIAL COMPLIANCE
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DOI：
10.1002/ccd.1810120604
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发表时间：
1986-01-01
期刊：
影响因子：
--
通讯作者：
RANDALL, OS
中科院分区：
文献类型：
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作者：
FERGUSON, JJ;RANDALL, OS
目前对于动脉顺应性的确切临床相关性还没有很好的理解。本研究的目的是确定哪些血流动力学变量与依从性最密切相关。对 41 名接受诊断性心导管插入术的患者进行了血流动力学测量。通过热稀释法测定心输出量，并用导管尖端压力计测量升主动脉的压力。顺应性是根据舒张压衰减压力的单指数拟合计算得出的。脉压（PP）、每搏输出量（SV）、年龄、收缩压（SBP）和心输出量（CO）与依从性显着相关。 SV/PP 商是对依从性的良好估计，SV 和 PP 的一阶函数也是如此。动脉顺应性似乎存在特定的临床相关性，以及在无法直接计算时基于传统血流动力学测量来估计动脉顺应性的方法。
There is at present no good understanding of the exact clinical correlates of arterial compliance. The purpose of this study was to establish which hemodynamic variables are most strongly associated with compliance. Hemodynamic measurements were performed on 41 patients undergoing diagnostic cardiac catheterization. Cardiac outputs were determined by thermodilution, and pressures were measured in the ascending aorta with a catheter‐tip manometer. Compliance was calculated from a mono‐exponential fit of diastolic decay pressures. Pulse pressure(PP), stroke volume(SV), age, systolic blood pressure(SBP), and cardiac output(CO) were significantly related to compliance. The quotient SV/PP was a good estimate of compliance, as was a first‐order function of both SV and PP. There appear to be specific clinical correlates of arterial compliance, as well as ways to estimate arterial compliance on the basis of conventional hemodynamic measurements when direct calculations are not possible.