The role of the motor cortex in the control of accuracy of locomotor movements in the cat.
The role of the motor cortex in the control of accuracy of locomotor movements in the cat.
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运动皮层在控制猫运动准确性方面的作用。
DOI：
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发表时间：
1993
期刊：
影响因子：
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通讯作者：
M. G. Sirota
中科院分区：
文献类型：
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作者：
I. Beloozerova;M. G. Sirota
1.在6只自由活动的成年猫中，使用可移动的清漆绝缘钨微电极在细胞外记录运动皮层（MC）中单个神经元的冲动活动。当猫在平坦的地板上行走时，当它们跨过一系列障碍物时，当它们在水平梯子的平坦梯级上行走时，神经元活动被记录下来。在10 - 100步内估计每个细胞中的平均放电速率（mR）和调频深度（dM）。2.在跨过间隔25 cm的屏障期间，记录了98个MC细胞（包括13个锥体束神经元（PTNs））的活性。在66%的mR和61%的这些细胞的dM变化超过20%，在运动与障碍相比，运动的单位（增加的情况更常见）。3.在跨过间隔12 cm的障碍物期间记录了9个细胞的活性，并且在与仅间隔6 cm的障碍物一起行走期间记录了27个细胞（包括5个PTN）的活性。在67%和59%的细胞中的mR，分别为56%和67%的细胞中的dM，分别在这些运动任务中比在平坦的运动中更大。4.在行走过程中记录了20个细胞的活性，并在不同距离的障碍物实验中进行了比较。当连续屏障之间的距离减小时，50%的神经元的mR和75%的神经元的dM进行性增加。5. 13个细胞的放电率进行了比较，在两个不同的运动任务：（i）当猫跨过障碍，需要过度屈曲的四肢和（ii）当它走在单位与负载连接到远端前肢引起的屈肌肌活动过度。9个细胞的活动是不同的，在跨越障碍的过程中相比，运动与负载的前肢。6.在沿着具有平坦横档的水平梯子沿着行走期间记录108个细胞（24个PTN）的活性。61%的mR和72%的dM的细胞在梯子上的运动过程中变化超过20%，与在平坦的（最常见的是他们增加）。7.在平地、障碍物或梯子上运动期间，大多数细胞（78 - 91%，取决于任务）的峰值频率相对于步进周期的位置没有差异。（400字处截断摘要）
1. The impulse activity of single neurones in the motor cortex (MC) was recorded extracellularly, using movable varnish‐insulated tungsten microelectrodes, in six adult, freely moving cats. Neuronal activity was recorded while the cats walked on a flat floor, as they stepped over a series of barriers, and as they walked on the flat rungs of a horizontal ladder. The mean discharge rate (mR) and the depth of frequency modulation (dM) in each cell were estimated over 10‐100 steps. 2. The activity of ninety‐eight MC cells (Including thirteen pyramidal tract neurones (PTNs)) was recorded during stepping over barriers 25 cm apart. The mR in 66% and the dM in 61% of these cells changed by more than 20% during locomotion with barriers compared to locomotion on the flat (an increase was more often the case). 3. The activity of nine cells was recorded during stepping over barriers 12 cm apart, and the activity of twenty‐seven cells (including five PTNs) during walking with barriers only 6 cm apart. The mR in 67% and in 59% of the cells, respectively, and the dM in 56% and in 67% of the cells, respectively, were greater in these locomotor tasks than during locomotion on the flat. 4. The activity of twenty cells was recorded during walking and compared in experiments with different distances between barriers. The mR in 50% and the dM in 75% of the neurones progressively increased when the distance between successive barriers was diminished. 5. The discharge rates of thirteen cells were compared in two different locomotor tasks: (i) when the cat stepped over barriers requiring hyperflexion of the limbs and (ii) when it walked on the flat with loads attached to the distal forelimbs causing a hyperactivity of flexor muscles. The activity of nine cells was different during stepping over the barriers compared to locomotion with loadings on the forelimbs. 6. The activity of 108 cells (twenty‐four PTNs) was recorded during walking along a horizontal ladder with flat rungs. The mR of 61% and the dM of 72% of cells changed by more than 20% during locomotion on the ladder compared with that on the flat (most often they increased). 7. The position of the peak rate relative to the step cycle did not differ in the majority of cells (in 78‐91% depending on the task) during locomotion on the flat, with the barriers or on the ladder.(ABSTRACT TRUNCATED AT 400 WORDS)