Biochemical characterization of avian T lymphocytespecific antigens

Biochemical characterization of avian T lymphocytespecific antigens
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禽类 T 淋巴细胞特异性抗原的生化特征

DOI:
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发表时间:
1981
影响因子:
5.4
通讯作者:
N. L. Le Douarin
N. L. Le Douarin
中科院分区:
医学3区
文献类型:
--
作者:
J. Pink;B. Fedecka‐Bruner;M. Coltey;B. Péault;N. L. Le Douarin

文献摘要

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Sera from rabbits injected with quail thymocytes were absorbed on quail bursal and liver cells. The absorbed sera reacted with avian T but not B lymphocytes in an immunofluorescence assay. Material precipitated by the anti‐T antisera from lysates of radioiodinated chicken or quail thymocytes was analyzed by one‐ and two‐dimensional electrophoresis. Of two anti‐T cell antisera studied in detail, one reacted mainly with a protein of an apparent molecular weight of 45000–55000, and the other with a protein of an apparent molecular weight 65000–70000. These proteins may be homologues of previously described mammalian T lymphocyte‐specific antigens.