STRUCTURE OF FLAVOENZYME GLUTATHIONE REDUCTASE
STRUCTURE OF FLAVOENZYME GLUTATHIONE REDUCTASE
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DOI：
10.1038/273120a0
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发表时间：
1978-01-01
期刊：
影响因子：
64.8
通讯作者：
PAI, EF
中科院分区：
文献类型：
--
作者：
SCHULZ, GE;SCHIRMER, RH;PAI, EF
通过0.3 nm分辨率的X射线衍射分析，通过X射线衍射分析阐明了二聚体黄酮人类红细胞谷胱甘肽还原酶[EC 1.6.4.2]的3维结构。追踪多肽链，并确定FAD，NADP和谷胱甘肽的结合位置。讨论了电子传输的机制。
The 3-dimensional structure of the dimeric flavoenzyme human erythrocyte glutathione reductase [EC 1.6.4.2] from human erythrocytes was elucidated by an X-ray diffraction analysis at 0.3 nm resolution. The polypeptide chain was traced, and the binding positions of FAD, NADP and glutathione were determined. A mechanism for the electron transfer is discussed.