Determinants of quality of life in patients with psoriasis: A study from the US population

Determinants of quality of life in patients with psoriasis: A study from the US population
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DOI:
10.1016/j.jaad.2004.04.014
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发表时间:
2004-11-01
影响因子:
13.8
通讯作者:
Margolis, DJ
Margolis, DJ
中科院分区:
医学1区
文献类型:
--
作者:
Gelfand, JM;Feldman, SR;Margolis, DJ

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背景:银屑病是一种对生活质量有实质性影响的常见病。从美国普通人群中对银屑病患者进行的生活质量研究很少。目的:描述美国人群中银屑病患者生活质量的决定因素。被医生诊断为银屑病的患者被邀请完成更详细的生活质量调查。结果:来自美国人口中的266名银屑病患者完成了详细的调查。身体表面积与生活质量下降的相关性最强(Spearman 0.50,P<.0001)。年轻患者和女性患者的生活质量在统计上也有显著下降。银屑病严重程度的增加与寻求多个医生的治疗和收入的减少有关。结论:皮肤受累范围越广的患者生活质量下降越大。女性患者和年轻患者受到的影响更大。
Background: Psoriasis is a common disease with substantial effects on quality of life. Few quality of life studies have been performed in psoriasis patients from the general US population.Objective: To describe the determinants of quality of life in psoriasis patients from the US population.Methods: Patients were randomly selected from the US population. Patients who identified themselves as having been diagnosed with psoriasis by a physician were invited to complete a more detailed survey about quality of life.Results: Two hundred sixty-six psoriasis patients from the US population completed the detailed survey. Body surface area showed the strongest association with decrements in quality of life (Spearman 0.50, P < .0001). Younger patients and female patients also had statistically significant reductions in quality of life. Increasing psoriasis severity was associated with seeking care from multiple physicians and having decrements in income.Conclusion: Patients with more extensive skin involvement have greater reductions in quality of life. Female patients and young patients are affected to a greater extent.