Prevalence of rheumatoid arthritis in the United States adult population in healthcare claims databases, 2004-2014
Prevalence of rheumatoid arthritis in the United States adult population in healthcare claims databases, 2004-2014
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DOI：
10.1007/s00296-017-3726-1
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发表时间：
2017-09-01
影响因子：
4
通讯作者：
Araujo, Andre B.
中科院分区：
文献类型：
--
作者：
Hunter, Theresa M.;Boytsov, Natalie N.;Araujo, Andre B.
本研究旨在确定2004年至2014年美国（US）成人投保人群中类风湿性关节炎的患病率。这是一项基于美国行政医疗保险索赔数据库（Truven Health MarketScan（A（R））Research数据库和IMS Pharaoh Plus数据库）的观察性、回顾性、横断面研究。使用经验证的RA识别算法分析了2004年1月1日至2014年12月31日10年期间RA患病率的趋势。确定数据库中的患病率，并预测2014年美国人口的年龄和性别调整率。两个数据库的数据分析表明，2004年至2014年，商业保险的美国成年人群的RA患病率范围为0.41%至0.54%。每年的患病率因性别和年龄而有很大差异，大多数亚组的患病率逐年逐渐增加。2014年，在Truven Health MarketScan（A（R））研究数据库中连续招募的31，316，902例成人患者中，157，634例（0.50%）患者符合我们的RA标准。同样，在IMS Pharmacy Plus数据库中的35，083，356例成人患者中，139，300例（0.50%）患者符合我们的RA标准。2014年，RA的总体年龄调整患病率范围为0.53%至0.55%（男性为0.29%至0.31%，女性为0.73%至0.78%）。2004年至2014年期间，美国RA的患病率似乎有所增加，2014年保守估计有128万至136万成年人受到影响。
This study aimed to determine the prevalence of rheumatoid arthritis in the United States (US) adult insured population from 2004 to 2014. This was an observational, retrospective, cross-sectional study based on US administrative health insurance claims databases (Truven Health MarketScan(A (R)) Research database and IMS PharMetrics Plus database). Trends in RA prevalence focusing on the 10-year period covering January 1, 2004-December 31, 2014 were analyzed using a validated algorithm for the identification of RA. Prevalence rates in the databases were determined and age- and gender-adjusted rates were projected to the US population in 2014. Analysis of data from the two databases indicated that the RA prevalence rate in commercially insured adult US population ranged from 0.41 to 0.54% from 2004 to 2014. The prevalence varied substantially by gender and age in each year and increased gradually across the years for most subgroups. In 2014, out of 31,316,902 adult patients with continuous enrollment in the Truven Health MarketScan(A (R)) Research database, 157,634 (0.50%) patients met our criteria for RA. Similarly, out of 35,083,356 adult patients in the IMS PharMetrics Plus database, 139,300 (0.50%) patients met our criteria for RA. In 2014, the overall age-adjusted prevalence of RA ranged from 0.53 to 0.55% (0.29-0.31% for males and 0.73-0.78% for females). The prevalence of RA in the US appeared to increase during the period from 2004 to 2014, affecting a conservative estimate of 1.28-1.36 million adults in 2014.