Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI.

Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI.
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DOI:
10.1016/j.amjmed.2010.07.023
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发表时间:
2011-01
影响因子:
5.9
通讯作者:
Goldberg, Robert J.
Goldberg, Robert J.
中科院分区:
医学2区
文献类型:
--
作者:
McManus, David D.;Gore, Joel;Yarzebski, Jorge;Spencer, Frederick;Lessard, Darleen;Goldberg, Robert J.

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尽管心电图改变被广泛用于表征急性心肌梗死患者,但对因急性心肌梗死入院的患者的发病率、治疗和结局的近期趋势知之甚少,根据ST段抬高的存在进一步分类。这项基于人群的研究的目的是检查马萨诸塞州大都会区中心居民中与2种主要类型急性心肌梗死相关的发病率和死亡率的近期趋势。我们回顾了1997年至2005年在11个大伍斯特医疗中心因ST段抬高急性心肌梗死(STEMI)或非ST段急性心肌梗死(NSTEMI)住院的伍斯特(MA)大都市区5,383名居民的病历。1997年至2005年,STEMI的发病率(每10万人)明显下降(121至77),而NSTEMI的发病率略有上升(126至132)。尽管两组的住院和30天病死率保持稳定,但STEMI和NSTEMI患者出院后1年的死亡率在1997年至2005年期间有所下降。本研究的结果表明,STEMI的幅度最近有所下降,NSTEMI的发病率略有增加,STEMI和NSTEMI患者的长期死亡率下降。我们的研究结果表明,急性心肌梗死的预防和治疗工作已导致STEMI的发生率和主要类型急性心肌梗死的死亡率下降。
Despite the widespread use of electrocardiographic changes to characterize patients presenting with acute myocardial infarction, little is known about recent trends in the incidence rates, treatment, and outcomes of patients admitted for acute myocardial infarction further classified according to the presence of ST-segment elevation. The objectives of this population-based study were to examine recent trends in the incidence and death rates associated with the 2 major types of acute myocardial infarction in residents of a large central Massachusetts metropolitan area. We reviewed the medical records of 5,383 residents of the Worcester (MA) metropolitan area hospitalized for either ST-segment elevation acute myocardial infarction (STEMI) or non-ST-segment acute myocardial infarction (NSTEMI) between 1997 and 2005 at 11 greater Worcester medical centers. The incidence rates (per 100,000) of STEMI declined appreciably (121 to 77), whereas the incidence rates of NSTEMI increased slightly (126 to 132), between 1997 and 2005. Although in-hospital and 30-day case-fatality rates remained stable in both groups, 1-year post discharge death rates declined between 1997 and 2005 for patients with STEMI and NSTEMI. The results of this study demonstrate recent declines in the magnitude of STEMI, slight increases in the incidence rates of NSTEMI, and declines in long-term mortality in patients with STEMI and NSTEMI. Our findings suggest that acute myocardial infarction prevention and treatment efforts have resulted in favorable declines in the frequency of STEMI and death rates from the major types of acute myocardial infarction.
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