Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)
Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)
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DOI：
10.1093/cid/ciy149
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发表时间：
2018-04-01
影响因子：
11.8
通讯作者：
Wilcox, Mark H.
中科院分区：
文献类型：
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作者：
McDonald, L. Clifford;Gerding, Dale N.;Wilcox, Mark H.
美国传染病学会（IDSA）和美国医疗保健流行病学学会（SHEA）召集了一个专家小组，对2010年成人艰难梭菌感染（CDI）临床实践指南进行更新。此次更新纳入了针对儿童的建议（遵循成人在流行病学、诊断和治疗方面的建议），包括在该感染的管理方面有重大变化，并反映出在最佳诊断方法上不断演变的争议。艰难梭菌仍然是医疗保健相关腹泻的最重要病因，并且已成为美国成人中最常被确定的医疗保健相关感染病因。此外，艰难梭菌已成为一种重要的社区病原体。尽管在欧洲部分地区，流行且有毒力的核糖体型027菌株的患病率随着艰难梭菌感染总体发病率的下降而显著下降，但它仍然是美国最常被确定的菌株之一，在美国它导致了相当一部分艰难梭菌感染，尤其是医疗保健相关的艰难梭菌感染。本指南更新了关于流行病学、诊断、治疗、感染预防和环境管理的建议。
A panel of experts was convened by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) to update the 2010 clinical practice guideline on Clostridium difficile infection (CDI) in adults. The update, which has incorporated recommendations for children (following the adult recommendations for epidemiology, diagnosis, and treatment), includes significant changes in the management of this infection and reflects the evolving controversy over best methods for diagnosis. Clostridium difficile remains the most important cause of healthcare-associated diarrhea and has become the most commonly identified cause of healthcare-associated infection in adults in the United States. Moreover, C. difficile has established itself as an important community pathogen. Although the prevalence of the epidemic and virulent ribotype 027 strain has declined markedly along with overall CDI rates in parts of Europe, it remains one of the most commonly identified strains in the United States where it causes a sizable minority of CDIs, especially healthcare-associated CDIs. This guideline updates recommendations regarding epidemiology, diagnosis, treatment, infection prevention, and environmental management.