Two distinct forms of functional lateralization in the human brain
Two distinct forms of functional lateralization in the human brain
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DOI：
10.1073/pnas.1302581110
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发表时间：
2013-09-03
影响因子：
11.1
通讯作者：
Martin, Alex
中科院分区：
文献类型：
--
作者：
Gotts, Stephen J.;Jo, Hang Joon;Martin, Alex
人类大脑中某些官能的半球偏侧化长期以来一直被认为对功能有益。然而，特定大脑区域的偏侧程度与功能水平之间的定量关系尚未建立。在这里，我们证明了两种不同形式的功能侧化存在于大脑的左半球和右半球，左半球表现出更倾向于与自身相互作用，特别是涉及语言和精细运动协调的皮质区域。相反，参与视觉空间和注意力处理的右半球皮层区域以一种更整合的方式与两个半球相互作用。这些不同系统中存在的侧化程度选择性地预测了语言和视觉空间能力的行为测量，为侧化与增强的认知能力相关提供了直接证据。
The hemispheric lateralization of certain faculties in the human brain has long been held to be beneficial for functioning. However, quantitative relationships between the degree of lateralization in particular brain regions and the level of functioning have yet to be established. Here we demonstrate that two distinct forms of functional lateralization are present in the left vs. the right cerebral hemisphere, with the left hemisphere showing a preference to interact more exclusively with itself, particularly for cortical regions involved in language and fine motor coordination. In contrast, right-hemisphere cortical regions involved in visuospatial and attentional processing interact in a more integrative fashion with both hemispheres. The degree of lateralization present in these distinct systems selectively predicted behavioral measures of verbal and visuospatial ability, providing direct evidence that lateralization is associated with enhanced cognitive ability.