Norovirus gastroenteritis.

Norovirus gastroenteritis.
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DOI:
10.1056/nejmra0804575
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发表时间:
2009-10-29
期刊:
The New England journal of medicine
影响因子:
--
通讯作者:
Estes MK
Estes MK
中科院分区:
其他
文献类型:
--
作者:
Glass RI;Parashar UD;Estes MK

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诺如病毒目前被认为是胃肠炎流行的主要原因,也是儿童和成人散发性胃肠炎的重要原因。在美国,超过90%的胃肠炎爆发,其原因以前不能确定,现在可以归因于这种病毒。了解对诺如病毒的免疫性质是未来改进这种病毒感染的控制和预防的关键决定因素。
Noroviruses are now recognized as the leading cause of epidemics of gastroenteritis and an important cause of sporadic gastroenteritis among both children and adults. In the United States, more than 90% of the outbreaks of gastroenteritis for which the cause could not previously be identified can now be attributed to this virus. Understanding the nature of immunity to the norovirus is a key determinant for future improvements in the control and prevention of this viral infection.