A "Connexin" Responsible for the Fatal Attraction of Cancer to Bone.
A "Connexin" Responsible for the Fatal Attraction of Cancer to Bone.
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DOI：
10.1016/j.cmet.2018.12.014
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发表时间：
2019-01
期刊：
影响因子：
29
通讯作者：
David L. Waning;T. Guise;K. Mohammad
中科院分区：
文献类型：
--
作者：
David L. Waning;T. Guise;K. Mohammad
肿瘤细胞与骨微环境的相互作用对于骨转移的建立和进展至关重要。最近，王等人在《癌细胞》中发表了文章。 (2018) 表明，成骨细胞谱系的细胞对于通过间隙连接将钙输送到肿瘤细胞至关重要，这为骨转移的潜在治疗指明了方向。
Tumor cell interactions with the bone microenvironment are vital for the establishment and progression of bone metastases. Recently inCancer Cell, Wang et al. (2018) showed that cells of the osteoblast lineage are critical for the delivery of calcium to tumor cells through gap junctions, pointing toward potential therapies for bone metastases.