Prevalence of glaucoma in rural Myanmar: the Meiktila eye study
Prevalence of glaucoma in rural Myanmar: the Meiktila eye study
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DOI：
10.1136/bjo.2006.107573
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发表时间：
2007-06-01
影响因子：
4.1
通讯作者：
Aung, T.
中科院分区：
文献类型：
--
作者：
Casson, J.;Newland, H. S.;Aung, T.
目的：确定缅甸中部农村密铁拉县青光眼的患病率。方法：对缅甸密铁拉县村庄 40 岁以上的居民进行横断面人口调查；确定了 2481 名符合条件的参与者，其中 2076 名参与者参与了该研究。眼科检查包括Snellen视力、裂隙灯检查、眼压测量、前房角镜检查、散瞳立体眼底检查和全阈值视野检查。青光眼分为临床亚型，并根据诊断证据分为三个级别。结果：1997（80.5%）参与者中诊断出青光眼。至少一只眼睛的任何类别青光眼的患病率为 4.9%（95% CI 4.1 至 5.7；n = 101）。原发性闭角型青光眼 (PACG) 的总体患病率为 2.5% (95% CI 1.5 - 3.5)，原发性开角型青光眼 (POAG) 的总体患病率为 2.0% (95% CI 0.9 - 3.1)。 PACG 占所有青光眼失明的 84%，其中大多数是由于急性闭角型青光眼 (AACG)。结论：缅甸中部农村地区 40 岁以上人群青光眼患病率为 4.9%。 PACG 与 POAG 的比率约为 1.25:1。 PACG 具有很高的视觉发病率，而 AACG 在这个社区中具有视觉破坏性。筛查计划应针对 PACG，并且需要在该人群中进一步研究 PACG 的潜在机制。
Aim: To determine the prevalence of glaucoma in the Meiktila district of central, rural Myanmar.Methods: A cross-sectional, population-based survey of inhabitants >= 40 years of age from villages in Meiktila district, Myanmar, was performed; 2481 eligible participants were identified and 2076 participated in the study. The ophthalmic examination included Snellen visual acuity, slit-lamp examination, tonometry, gonioscopy, dilated stereoscopic fundus examination and full-threshold perimetry. Glaucoma was classified into clinical subtypes and categorised into three levels according to diagnostic evidence.Results: Glaucoma was diagnosed in 1997 (80.5%) participants. The prevalence of glaucoma of any category in at least one eye was 4.9% (95% CI 4.1 to 5.7; n = 101). The overall prevalence of primary angle-closure glaucoma (PACG) was 2.5% (95% CI 1.5 to 3.5) and of primary open-angle glaucoma (POAG) was 2.0% (95% CI 0.9 to 3.1). PACG accounted for 84% of all blindness due to glaucoma, with the majority due to acute angle-closure glaucoma (AACG).Conclusion: The prevalence of glaucoma in the population aged >= 40 years in rural, central Myanmar was 4.9%. The ratio of PACG to POAG was approximately 1.25:1. PACG has a high visual morbidity and AACG is visually devastating in this community. Screening programmes should be directed at PACG, and further study of the underlying mechanisms of PACG is needed in this population.