New field with tonotopic organization in guinea pig auditory cortex
New field with tonotopic organization in guinea pig auditory cortex
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DOI：
10.1152/jn.00689.2006
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发表时间：
2007-01-01
影响因子：
2.5
通讯作者：
Song, Wen-Jie
中科院分区：
文献类型：
--
作者：
Nishimura, Masataka;Shirasawa, Hiroshi;Song, Wen-Jie
豚鼠听觉皮层中具有音调结构的新领域。J Neurophysiol 97：927 - 932，2007. 2006年10月18日首次出版; doi：10.1152/jn. 00689.2006.在豚鼠听觉皮层中，两个核心区，一个初级区（AI）和一个背尾区（DC），和两个带区腹侧的AI和DC（VRB和VCB）之间的一个中间区（T），以及一个小的字段（S）吻到AI，已在单电极研究中报告，虽然场S和T区尚未在成像研究中观察到。使用高分辨率的在体光学成像系统与电压敏感染料RH-795，我们在这里报告的成功成像的吻侧小字段和T区和腹到背的频率梯度在T区。此外，我们发现，VRB可以细分为两个领域，一个ventroorostral场（VR）的性质类似的VRB报告，和一个ventrocaudal场（VC）的新属性。随着刺激频率的增加，VR的激活向尾侧移动，而VC的激活向喙侧移动。因此，我们有新的领域VC，具有镜像对称tonotopy的VR。
New field with tonotopic organization in guinea pig auditory cortex. J Neurophysiol 97: 927 - 932, 2007. First published October 18, 2006; doi:10.1152/jn. 00689.2006. In guinea pig auditory cortex, two core areas, a primary area (AI) and a dorsocaudal field (DC), and two belt regions ventral to AI and DC (VRB and VCB) with an intermediate zone (T) in between, together with a small field (S) rostral to AI, have been reported in single-electrode studies although field S and zone T have not been observed in imaging studies. Using a high-resolution in vivo optical-imaging system with the voltage-sensitive dye RH-795, we report here the successful imaging of a rostral small field and zone T and a ventral-to-dorsal frequency gradient in zone T. Further, we found that VRB can be subdivided into two areas, a ventrorostral field (VR) with properties similar to those reported for VRB, and a ventrocaudal field (VC) with novel properties. With increasing stimulus tone frequency, activation in VR shifted caudally while activation in VC shifted rostrally. Thus we have newly identified field VC that has mirror-symmetric tonotopy to that of VR.