Sex and race influence objective and self-report sleep and circadian measures in emerging adults independently of risk for bipolar spectrum disorder.
Sex and race influence objective and self-report sleep and circadian measures in emerging adults independently of risk for bipolar spectrum disorder.
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性别和种族影响新兴成年人的客观和自我报告的睡眠和昼夜节律测量，与双相谱系障碍的风险无关。
DOI：
10.1038/s41598-020-70750-3
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发表时间：
2020
影响因子：
4.6
通讯作者：
Alloy,LaurenB
中科院分区：
文献类型：
--
作者：
Titone,MadisonK;McArthur,BraeAnne;Ng,TommyH;Burke,TaylorA;McLaughlin,LauraE;MacMullen,LauraE;Goel,Namni;Alloy,LaurenB
有必要更好地了解影响不同种族和性别年轻人睡眠和昼夜节律功能的关键因素。性别和种族是造成健康结果差异的常见因素；然而，这些变量对年轻人睡眠和昼夜节律模式的影响还不是很清楚。在一项生态瞬时评估研究中，对150名患有双相情感障碍高风险或低风险的新兴成年人(MAGE= 21.8%，女性58.7%，白人56%，黑人22.7%，其他种族21.3%)进行了睡眠和昼夜节律功能的多个客观和自我报告方面的评估(褪黑素发作、活动记录和睡眠日记)。控制BSD风险状态、性别和种族是客观和自我报告的睡眠和昼夜节律测量的重要预测因素。男性自我报告的睡眠效率比女性更高，并且表现出比女性更晚的暗光褪黑素起始期，而女性表现出更多的活动测量睡眠时间。与黑人参与者相比，白人参与者表现出更多的活动测量的总睡眠时间(TST)，更好的睡眠效率，更少的睡眠时间，更多的自我报告的TST和更好的睡眠效率。我们的发现通过利用对睡眠和昼夜节律参数的稳健测量来加强文献，将先前的发现扩展到患有BSD的高风险或低风险的年轻人样本。
There is a need to better understand key factors that impact sleep and circadian function for young adults of differing races and sexes. Sex and race are common factors contributing to disparities in health outcomes; however, the influence of these variables on sleep and circadian patterns for young adults are not well known. Multiple objective and self-report facets of sleep and circadian function were assessed (melatonin onset, actigraphy, and sleep diaries) in an ecological momentary assessment study of 150 emerging adults (Mage= 21.8 years; 58.7% female; 56% White, 22.7% Black, 21.3% Other ethnicity) at high or low risk for bipolar spectrum disorder (BSD). Controlling for BSD risk status, sex and race were significant predictors of objective and self-reported sleep and circadian rhythm measures. Males self-reported better sleep efficiency and exhibited later dim light melatonin onset phase than females, whereas females exhibited more actigraphy-measured sleep periods. White participants exhibited more actigraphy-measured total sleep time (TST), better sleep efficiency, and fewer sleep periods, and more self-reported TST and better sleep efficiency than Black participants. Our findings enhance the literature by utilizing robust measurement of sleep and circadian parameters to extend previous findings to a young adult sample at high or low risk for BSD.