σs-dependent regulation of yehZYXW, which encodes a putative osmoprotectant ABC transporter of Escherichia coli
σs-dependent regulation of yehZYXW, which encodes a putative osmoprotectant ABC transporter of Escherichia coli
复制标题
DOI：
10.1016/j.femsle.2004.05.046
复制
发表时间：
2004-07-15
影响因子：
2.1
通讯作者：
Gutierrez, C
中科院分区：
文献类型：
--
作者：
Checroun, C;Gutierrez, C
大肠杆菌 yehZYXW 操纵子编码 ABC 转运蛋白家族的假定渗透保护剂摄取系统。 yehZ 与 osmF 相同，osmF 是先前鉴定的渗透诱导基因。 yehZ-lacZ 转录融合体的构建和分析表明，yehZ 不仅可以通过渗透压诱导，而且可以在进入稳定期时诱导。渗透压和生长期调节在独特的启动子 yehZp 上运行，并且完全依赖于胁迫特异性 sigma 因子 sigma。 yehZYXW 编码的 ABC 转运蛋白似乎是由 sigma 控制的全局应激反应的附加元素。 (C) 2004 年欧洲微生物学会联合会。由 Elsevier B.V. 出版。保留所有权利。
The Escherichia coli yehZYXW operon encodes a putative osmoprotectant uptake system of the ABC transporter family. yehZ is identical to osmF, an osmotically inducible gene identified previously. Construction and analysis of a yehZ-lacZ transcriptional fusion demonstrated that yehZ is inducible not only by osmolarity, but also upon entry into stationary phase. The osmotic and growth-phase regulations operate at a unique promoter, yehZp, and are totally dependent on the stress specific sigma factor sigma(s). The yehZYXW encoded ABC transporter appears as an additional element of the global stress response controlled by sigma(s). (C) 2004 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.