EFFECT OF RECIPIENT-DONOR TREPHINE SIZE DISPARITY ON REFRACTIVE ERROR IN KERATOCONUS
EFFECT OF RECIPIENT-DONOR TREPHINE SIZE DISPARITY ON REFRACTIVE ERROR IN KERATOCONUS
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DOI：
10.1016/s0161-6420(89)32896-x
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发表时间：
1989-03-01
期刊：
影响因子：
13.7
通讯作者：
BOURNE, WM
中科院分区：
文献类型：
--
作者：
WILSON, SE;BOURNE, WM
本研究旨在探讨供受者环钻差异对圆锥角膜术后屈光不正及角膜曲率去除的影响。采用双线缝合技术，供体角膜从内皮侧环切。供体比供体环钻大0.2 5 mm的圆锥角膜患者与相同大小的供体和供体环钻的圆锥角膜患者相比，平均角膜曲率计值(分别为45.4和43.8 D，P=0.0 3)和近视等效球镜(分别为−3.5和−1.8D，P=0.0 3)显著增加。圆锥角膜患者与Phakic Fuchs营养不良患者(两组都有0.25 mm超大供体环钻)相比，近视球镜等效值(分别为−3.5D和−1.4D；P=0.03)显著高于Phakic Fuchs营养不良患者(分别为45.4D和44.7D)，但差异无统计学意义(分别为45.4D和44.7D)。这项研究支持这样的假设，即圆锥角膜患者的穿透性角膜移植后近视程度可以通过减少受者-供者环钻的差异来降低。
A retrospective study was performed to evaluate the effect of recipient-donor trephine disparity on refractive error and corneal curvature postsuture removal in keratoconus. A double running suture technique was used and donor corneas were trephined from the endothelial side. When keratoconus patients with 0.25-mm larger donor than recipient trephines were compared with keratoconus patients with the same size recipient and donor trephines, a statistically significant increase in the mean keratometer value (45.4 and 43.8 diopters [D], respectively;P= 0.03) and increase in myopic spherical equivalent (−3.5 and −1.8 D, respectively;P= 0.03) was found. When keratoconus patients were compared with phakic Fuchs' dystrophy patients (both groups had 0.25mm oversize donor trephines), the keratoconus group had a statistically significantly higher myopic spherical equivalent (−3.5 and −1.4 D, respectively;P= 0.03) despite only a 0.7-D difference in mean keratometer value which was not statistically significant (45.4 and 44.7 D, respectively). This study supports the hypothesis that the degree of post-penetrating keratoplasty myopia in patients with keratoconus can be decreased by reducing recipient-donor trephine disparity.