Parameters impacting the live birth rate per transfer after frozen single euploid blastocyst transfer

Parameters impacting the live birth rate per transfer after frozen single euploid blastocyst transfer
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DOI:
10.1371/journal.pone.0227619
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发表时间:
2020-01-13
期刊:
影响因子:
3.7
通讯作者:
Bahceci, Mustafa
Bahceci, Mustafa
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Boynukalin, Fazilet Kubra;Gultomruk, Meral;Bahceci, Mustafa

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背景评估患者特征、受控卵巢刺激和胚胎学参数对单整倍体冻温囊胚移植 (FBT) 活产结果的预测价值。方法这是一项回顾性队列研究,包括 2015 年 10 月 1 日至 2018 年 1 月 1 日进行的植入前非整倍体基因检测 (PGT-A) 后的 707 个单 FBT。患者、周期和胚胎学相关的影响结果在基于活产的亚组分析中,实现活产的患者的体重指数(BMI)显着低于未实现活产的患者(22.7(21.5-24.6)kg/m(2) vs 27(24-29.2)kg/m(2),p
BackgroundTo assess the predictive value of patient characteristics, controlled ovarian stimulation and embryological parameters on the live birth outcome of single euploid frozen-warmed blastocyst transfer (FBT).MethodsThis was a retrospective cohort study including 707 single FBTs after preimplantation genetic testing for aneuploidy (PGT-A) that were performed from October 1, 2015, to January 1, 2018. The effects of patient-, cycle-and embryology-related parameters on the live birth outcome after FBT were assessed.ResultsIn the subgroup analysis based on live birth, patients who achieved a live birth had a significantly lower body mass index (BMI) than patients who did not achieve a live birth (22.7 (21.5-24.6) kg/m(2) vs 27 (24-29.2) kg/m(2), p