Comparison of subfoveal choroidal thickness in eyes with CRVO and BRVO

Comparison of subfoveal choroidal thickness in eyes with CRVO and BRVO
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CRVO 和 BRVO 眼中心凹下脉络膜厚度的比较。

DOI:
10.1186/s12886-019-1143-9
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发表时间:
2019-06-21
期刊:
影响因子:
2
通讯作者:
Chen, Qi
Chen, Qi
中科院分区:
医学4区
文献类型:
--
作者:
Tang, Fen;Xu, Fan;Chen, Qi

文献摘要

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目的评价视网膜静脉阻塞(RVO)继发黄斑水肿(ME)患者黄斑中心凹下脉络膜厚度(SFCT)的变化,并观察单次玻璃体腔注射雷珠单抗(IVR)后的近期疗效。方法回顾性分析36 6例初治的RVO继发单侧ME患者(CRVO 19例,BRVO 17例)的SFCT和SFCT变化。所有患者初诊后均接受IVR注射。在IVR注射开始时和2周后测量SFCT。采用配对t检验比较RVO眼与对侧眼的SFCT以及注射前后的SFCT。结果CRVO患眼SFCT平均值为326.03 ± 30.86m,明显大于对侧患眼(P
BackgroundTo evaluate the subfoveal choroidal thickness (SFCT) in eyes with macular edema (ME) secondary to retinal vein occlusion(RVO), and to investigate the short term response after a single intravitreal ranibizumab (IVR) injection. What is more, to compare SFCT and SFCT change between central RVO (CRVO) and branch RVO (BRVO).MethodsIn the retrospective study, we had collected 36-six treatment-naive patients with unilateral ME secondary to RVO (including 19 CRVO and 17 BRVO). All patients had received IVR injection after newly diagnosed. The SFCT was measured at the onset and after 2 weeks of IVR injection. Paired t test was performed to compare the SFCT of RVO eyes and fellow eyes, as well as the SFCT of pre-injection and post-injection. In further, independent t test was used to compare SFCT and SFCT change between CRVO eyes and BRVO eyes.ResultsThe mean SFCT at the onset was 326.0330.86m in CRVO eyes, which was significantly thicker than that in contralateral fellow eyes (p