Outcome measures report different aspects of patient function three months following critical care

Outcome measures report different aspects of patient function three months following critical care
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DOI:
10.1007/s00134-014-3513-3
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发表时间:
2014-12-01
影响因子:
38.9
通讯作者:
Moss, Marc
Moss, Marc
中科院分区:
医学1区
文献类型:
--
作者:
Denehy, Linda;Nordon-Craft, Amy;Moss, Marc

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以往对重症监护病房(ICU)幸存者的体能与患者自我报告的身体功能(PF)指标之间关系的研究尚未进行,目的:(1)分析其他基于活动的体能指标在多大程度上可作为6分钟步行试验(6 MWT)的替代指标;(2)确定简明量表(SF)36 PF和身体成分汇总(PCS)评分的范围,反映身体机能的组成部分和(3)检查人口统计学和ICU变量与6 MWT之间的关系。两个临床试验的截面数据。两个急性护理医院(墨尔本,澳大利亚和丹佛,美国)。共177名ICU幸存者。在3个月进行了评估。基于业绩的措施包括:6 MWT、定时起立和行走测试(TUG)、5次坐立测验(5xSTS)、贝格平衡量表(BBS)和两项自我报告测量:SF-36 PF域和PCS评分。6 MWT与TUG显示出良好的相关性(rho = -0.79)和BBS(rho = 0.80);与5xSTS(rho = -0.69)和SF-36 PF评分(rho = 0.69)具有良好相关性。6 MWT分别解释了SF-36、PF和PCS评分的54%和33%的变异。6 MWT和TUG均可作为预测术后3个月PF功能的指标。基于表现的测试测量不同的结构比自我报告的措施和结果变量的选择应符合研究目的,以确保使用最适当的措施。
Previous investigation of the relationship between physical performance and patient self-report physical function (PF) measures in intensive care unit (ICU) survivors have not been performed.To (1) analyze the extent to which other activity-based measures of physical performance may serve as proxies for the 6-min walk test (6MWT); (2) determine the extent to which the Short Form (SF) 36 domain of PF and physical component summary (PCS) score, reflect components of physical performance and (3) examine the relationship between demographic and ICU variables and the 6MWT.Cross-sectional data from two clinical trials.Two acute care hospitals (Melbourne, Australia and Denver, USA).A total of 177 survivors of ICU.Were evaluated at 3 months. Performance-based measures were: 6MWT, timed up and go test (TUG), the five times sit to stand test (5xSTS), the Berg balance scale (BBS) and two self-report measures: the SF-36 PF domain and the PCS score.6MWT showed excellent correlation with the TUG (rho = -0.79) and BBS (rho = 0.80); and good correlation with 5xSTS (rho = -0.69) and SF-36 PF scores (rho = 0.69). 6MWT explained 54 and 33 % of variance in SF-36 PF and PCS scores respectively. No variables were clinically important in predicting 6MWT.The 6MWT and TUG may both be acceptable measures of PF performance 3 months after ICU. Performance-based tests measure different constructs than self-report measures and choice of outcome variables should be aligned with study aims to ensure the most appropriate measure is used.