Scrub typhus in Japan: Epidemiology and clinical features of cases reported in 1998
Scrub typhus in Japan: Epidemiology and clinical features of cases reported in 1998
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DOI：
10.4269/ajtmh.2002.67.162
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发表时间：
2002-08-01
影响因子：
3.3
通讯作者：
Masukawa, K
中科院分区：
文献类型：
--
作者：
Ogawa, M;Hagiwara, T;Masukawa, K
1998年在日本使用问卷调查对恙虫病进行了监测。共报告了462例病例。在本州（主岛）的北方，恙虫病在秋季和春季都有发生，在本州中部和九州岛，恙虫病在秋季也有发生。该病的发生随年龄、性别和活动而变化。76%的患者年龄在51岁以上，分别有36%和16%的患者从事农业和林业工作。分别在98%、93%和97%的患者中检测到发热、皮疹和焦痂。在96%、87%和77%的患者中分别检测到C反应蛋白、天冬氨酸转氨酶和丙氨酸转氨酶水平升高。弥散性血管内凝血34例，有独特的区域分布。这项研究显示了1998年日本恙虫病的状况，为诊断和预防提供了重要信息。
Surveillance for scrub typhus was conducted in Japan in 1998 using a questionnaire. A total of 462 cases were reported. Scrub typhus occurred in both the fall and spring in the northern part of Honshu (the main island), and in the fall in the central part of Honshu and on the island of Kyushu. The occurrence of the disease varied with age, gender, and activity. Seventy-six percent of the patients were more than 51 years old, and 36% and 16% of the patients were engaged in farm work and forestry, respectively. Fever, rash, and eschar were detected in 98%, 93%, and 97% of the patients, respectively. Elevated levels of C-reactive protein, aspartate transaminase, and alanine transaminase were detected in 96%, 87%, and 77% of the patients, respectively. Disseminated intravascular coagulation developed in 34 cases and had a unique regional distribution. This study shows the status of scrub typhus in Japan in 1998 and provides important information for diagnosis and prevention.