Neuronal activity in the medulla oblongata during vocalization.: A single-unit recording study in the squirrel monkey
Neuronal activity in the medulla oblongata during vocalization.: A single-unit recording study in the squirrel monkey
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DOI：
10.1016/s0166-4328(00)00272-2
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发表时间：
2000-12-05
影响因子：
2.7
通讯作者：
Jürgens, U
中科院分区：
文献类型：
--
作者：
Lüthe, L;Häusler, U;Jürgens, U
在6只松鼠猴(Saimiri Oriureus)身上，用微电极探查延髓，寻找与发声相关的活动。这些发声是通过向中脑导水管周围灰质微量注射谷氨酸激动剂而引起的。发声相关细胞在核团中大量存在。在小细胞、大细胞和中央网状结构以及孤束核和三叉神经脊束核。前庭复合体、楔状核、下橄榄核和外侧网状核也有少量分布。将神经元反应区分为12种反应类型表明，每种反应类型的频率随大脑结构的不同而不同，从而可以指定与发声相关的不同区域。根据这一规范，提出发声的起始是通过小细胞网状结构进行的；发声模式的控制主要由小细胞网状结构、Ab、孤束核和三叉神经脊束核实现；呼气控制和呼吸-喉部的协调是由网状结构的Rab、Ab和中央核进行的；发声特有的姿势调整通过前庭和楔状核进行。(C)2000 Elsevier Science B.V.保留所有权利。
In six squirrel monkeys (Saimiri sciureus), the medulla oblongata was explored with microelectrodes, looking for vocalization-correlated activity. The vocalizations were elicited by microinjections of glutamate agonists into the periaqueductal grey of the midbrain. Vocalization-related cells were found in greater numbers in the nucl. ambiguus (Ab) and retroambiguus (RAb), in the parvocellular, magnocellular and central reticular formation as well as in the solitary tract nucleus and spinal trigeminal nucleus. Small numbers were also found in the vestibular complex, cuneate nuclei, inferior olive and lateral reticular nucleus. A differentiation of the neuronal responses into 12 reaction types reveals that the frequency of each reaction type varies from brain structure to brain structure, thus allowing a specification of the different vocalization-related areas. According to this specification, it is proposed that initiation of vocalization takes place via the parvocellular reticular formation; vocal pattern control is mainly brought about by the parvocellular reticular formation, Ab, solitary tract nucleus and spinal trigeminal nucleus; expiratory control and respiratory-laryngeal coordination is carried out by the RAb, Ab and central nucleus of the reticular formation; vocalization-specific postural adjustments are carried out via the vestibular and cuneate nuclei. (C) 2000 Elsevier Science B.V. All rights reserved.