Prevalence of Frailty in Community-Dwelling Older Persons: A Systematic Review
Prevalence of Frailty in Community-Dwelling Older Persons: A Systematic Review
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DOI：
10.1111/j.1532-5415.2012.04054.x
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发表时间：
2012-08-01
影响因子：
6.3
通讯作者：
Voshaar, Richard C. Oude
中科院分区：
文献类型：
--
作者：
Collard, Rose M.;Boter, Han;Voshaar, Richard C. Oude
目标 根据性别、年龄和所使用的衰弱定义，系统地比较和汇总社区老年人中报告的衰弱（包括衰弱前期）的患病率。设计 使用关键词老年、老年、虚弱、患病率和流行病学对文献进行系统回顾。设置来自社区群体的横截面数据。参与者 65 岁及以上的社区居民成年人。测量 在发现的研究中，衰弱和衰弱前期是根据身体表型和广泛表型来测量的，第一个将衰弱定义为纯粹的身体状况，第二个还包括心理社会方面。结果 社区报告的患病率差异很大（范围 4.059.1%）。虚弱的总体加权患病率为 10.7%（95% 置信区间 (CI) = 10.510.9；21 项研究；61,500 名参与者）。身体虚弱的加权患病率为 9.9%（95% CI = 9.610.2；15 项研究；44,894 名受试者），虚弱的广泛表型的加权患病率为 13.6%（95% CI = 13.214.0；8 项研究；24,072 名受试者）（卡方 (chi(2)) = 217.7，自由度(df)=1, P < .001）。患病率随着年龄的增长而增加（chi(2) = 6067，df = 1，P < .001），并且女性的患病率（9.6%，95% CI = 9.210.0%）高于男性（5.2%，95% CI = 4.95.5%；chi(2) = 298.9 df = 1，P < .001）。结论 衰弱在晚年很常见，但衰弱状态的不同操作导致研究之间的患病率存在很大差异。提高流行病学和临床研究的可比性是向前迈出的重要一步。
Objectives To systematically compare and pool the prevalence of frailty, including prefrailty, reported in community-dwelling older people overall and according to sex, age, and definition of frailty used. Design Systematic review of the literature using the key words elderly, aged, frailty, prevalence, and epidemiology. Setting Cross-sectional data from community-based cohorts. Participants Community-dwelling adults aged 65 and older. Measurements In the studies that were found, frailty and prefrailty were measured according to physical phenotype and broad phenotype, the first defining frailty as a purely physical condition and the second also including psychosocial aspects. Results Reported prevalence in the community varies enormously (range 4.059.1%). The overall weighted prevalence of frailty was 10.7% (95% confidence interval (CI) = 10.510.9; 21 studies; 61,500 participants). The weighted prevalence was 9.9% for physical frailty (95% CI = 9.610.2; 15 studies; 44,894 participants) and 13.6% for the broad phenotype of frailty (95% CI = 13.214.0; 8 studies; 24,072 participants) (chi-square (chi(2)) = 217.7, degrees of freedom (df)=1, P < .001). Prevalence increased with age (chi(2) = 6067, df = 1, P < .001) and was higher in women (9.6%, 95% CI = 9.210.0%) than in men (5.2%, 95% CI = 4.95.5%; chi(2) = 298.9 df = 1, P < .001). Conclusion Frailty is common in later life, but different operationalization of frailty status results in widely differing prevalence between studies. Improving the comparability of epidemiological and clinical studies constitutes an important step forward.