Characterization of Traveling Wave Ion Mobility Separations in Structures for Loss less Ion Manipulations
Characterization of Traveling Wave Ion Mobility Separations in Structures for Loss less Ion Manipulations
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DOI：
10.1021/acs.analchem.5b02481
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发表时间：
2015-11-17
影响因子：
7.4
通讯作者：
Smith, Richard D.
中科院分区：
文献类型：
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作者：
Hamid, Ahmed M.;Ibrahim, Yehia M.;Smith, Richard D.
我们报告的发展和表征的行波（TVV）为基础的无损离子操作（TW-SLIM）模块的离子迁移率分离（IMS）的结构。TVV-SLIM模块在两个紧密间隔的表面上使用平行的rf电极阵列进行离子约束，其中rf电极被短电极阵列分开，并且可以使用这些TVsT来驱动离子运动。在这一初步工作中，TVVs是由直流电位的动态应用。TW-SLIM模块的有效离子约束，无损离子传输，和离子迁移率分离在不同的RF和TVV参数的能力进行了报道。TW-SLIM模块被示出为利用限制RF波形（类似于1 MHz和300 Vp.p）和低TW振幅（
We report on the development and characterization of a traveling wave (TVV)-based Structures for Loss less Ion Manipulations (TW-SLIM) module for ion mobility separations (IMS). The TVV-SLIM module uses parallel arrays of rf electrodes on two closely spaced surfaces for ion confinement, where the rf electrodes are separated by arrays of short electrodes, and using these TVsTs can be created to drive ion motion. In this initial work, TVVs are created by the dynamic application of dc potentials. The capabilities of the TW-SLIM module for efficient ion confinement, lossless ion transport, and ion mobility separations at different rf and TVV parameters are reported. The TW-SLIM module is shown to transmit a wide mass range of ions (m/z 200-2500) utilizing a confining rf waveform (similar to 1 MHz and,300 Vp.p) and low TW amplitudes (