Emerging micro- and nanotechnologies in cancer diagnosis and therapy.
Emerging micro- and nanotechnologies in cancer diagnosis and therapy.
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癌症诊断和治疗中的新兴微米和纳米技术。
DOI：
10.1007/s10544-013-9785-5
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发表时间：
2013
影响因子：
2.8
通讯作者：
Khademhosseini,Ali
中科院分区：
文献类型：
--
作者：
Zhang,JohnXJ;Khademhosseini,Ali
了解癌细胞转移的机制对于癌症的靶向诊断和研究至关重要。但这一过程仍未完全被理解，主要是因为缺乏精确模拟癌细胞血管内流动、侵袭、粘附、转移、血管生成和迁移到特定部位的生理复杂性的体外细胞培养模型。微米级和纳米级技术为此目的提供了一个有前途的工具。本期特刊广泛涵盖细胞微环境、生物表面修饰、多功能纳米粒子和纳米传感器、微流体、分子检测以及癌症的多阶段靶向策略等主题。特别是，它侧重于研究如何利用微米和纳米技术的力量从根本上改变我们诊断和治疗癌症的方式。这包括两者
Understanding the mechanism of cancer cell metastasis is crucial for targeted cancer diagnosis and research. But this process is still not fully understood mainly because of lack of in vitro cell culture models that precisely mimic the physiological complexities of cancer cell intravascular flows, invasion, adhesion, metastasis, angiogenesis and migration to specific sites. Micro-and nanoscale technologies offer a promising tool for such purpose.This special issue broadly covers the topics of cell microenvironment, biological surface modifications, multifunctional nanoparticles and nanosensors, microfluidics, molecular detection as well as multistage targeting strategies for cancer. In particular, it focuses on investigating how we can harness the power of micro-and nanotechnologies to radically change the way we diagnose and treat cancer. This includes both