Three-Dimensional Photoacoustic Imaging Using a Two-Dimensional CMUT Array
Three-Dimensional Photoacoustic Imaging Using a Two-Dimensional CMUT Array
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DOI：
10.1109/tuffc.2009.1329
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发表时间：
2009-11-01
影响因子：
3.6
通讯作者：
Khuri-Yakub, Butrus T.
中科院分区：
文献类型：
--
作者：
Vaithilingam, Srikant;Ma, Te-Jen;Khuri-Yakub, Butrus T.
在本文中，我们描述了使用2-D阵列的电容式微机械超声换能器（CMUT）进行3-D光声和声成像。利用可调谐光参量振荡器产生纳秒级激光脉冲来诱导光声信号。为了证明系统的可行性，对2个不同的体模进行成像。第一个体模由直径分别为180 μ m和150 μ m的黑色和透明鱼线交替组成。第二个体模包括聚乙烯管，嵌入鸡胸组织中，充满液体，如染料吲哚菁绿色、猪血和两者的混合物。将管嵌入组织内0.8 cm的深度处，并且与CMUT阵列的总距离为1.8 cm。二维横截面切片和3-D体积呈现图像的脉冲回波数据，以及光声数据。钓鱼线的轮廓和波束宽度进行了分析，并与使用Field II超声模拟软件进行的数值模拟进行比较。我们研究了使用大孔径（64 x 64元件阵列）通过机械扫描较小的CMUT阵列（16 x 16元件）来执行光声和声学成像。二维换能器阵列克服了机械扫描系统的许多限制，并实现了体积成像。用于光声成像的CMUT技术的优点包括易于与电子器件集成，能够制造具有任意几何形状的大型完全填充的2-D阵列，宽带宽阵列和高频阵列。提出了一种基于CMUT的光声系统作为压电换能器的光声系统的可行替代方案。
In this paper, we describe using a 2-D array of capacitive micromachined ultrasonic transducers (CMUTs) to perform 3-D photoacoustic and acoustic imaging. A tunable optical parametric oscillator laser system that generates nanosecond laser pulses was used to induce the photoacoustic signals. To demonstrate the feasibility of the system, 2 different phantoms were imaged. The first phantom consisted of alternating black and transparent fishing lines of 180 mu m and 150 mu m diameter, respectively. The second phantom comprised polyethylene tubes, embedded in chicken breast tissue, filled with liquids such as the dye indocyanine green, pig blood, and a mixture of the 2. The tubes were embedded at a depth of 0.8 cm inside the tissue and were at an overall distance of 1.8 cm from the CMUT array. Two-dimensional cross-sectional slices and 3-D volume rendered images of pulse-echo data as well as photoacoustic data are presented. The profile and beam-widths of the fishing line are analyzed and compared with a numerical simulation carried out using the Field II ultrasound simulation software. We investigated using a large aperture (64 x 64 element array) to perform photoacoustic and acoustic imaging by mechanically scanning a smaller CMUT array (16 x 16 elements). Two-dimensional transducer arrays overcome many of the limitations of a mechanically scanned system and enable volumetric imaging. Advantages of CMUT technology for photoacoustic imaging include the ease of integration with electronics, ability to fabricate large, fully populated 2-D arrays with arbitrary geometries, wide-bandwidth arrays and high-frequency arrays. A CMUT based photoacoustic system is proposed as a viable alternative to a piezoelectric transducer based photoacoustic systems.