Leptin as clinical target.
Leptin as clinical target.
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DOI：
10.2174/187221309789257379
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发表时间：
2009-10
影响因子：
4.2
通讯作者：
Chunlin Cai;Fu Dong Shi;G. Matarese;A. Cava
中科院分区：
文献类型：
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作者：
Chunlin Cai;Fu Dong Shi;G. Matarese;A. Cava
PLeptin是一种脂肪细胞来源的激素，对能量稳态、内分泌和生殖功能以及免疫反应具有多效性作用。瘦素的多重作用导致了几种基于瘦素的方法的设计和开发，以调节代谢和内分泌状态，减少炎症，并改善免疫反应。本文就瘦素在不同临床应用中的专利进行综述。
PLeptin is an adipocyte-derived hormone with pleiotropic effects on energy homeostasis, endocrine and reproductive functions, and immune responses. The multiple actions of leptin have led to the design and development of several leptin-based approaches to modulate the metabolic and endocrine status, to reduce inflammation, and to improve immune responses. Here, we review the current patents on leptin in different clinic applications.