Chirality-dependent halogen bonds in axially chiral quinazolin-4-one derivatives bearing ortho-halophenyl groups
Chirality-dependent halogen bonds in axially chiral quinazolin-4-one derivatives bearing ortho-halophenyl groups
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DOI：
10.1039/c9ce00320g
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发表时间：
2019-06-14
期刊：
影响因子：
3.1
通讯作者：
Kitagawa, Osamu
中科院分区：
文献类型：
--
作者：
Imai, Tomomi;Niijima, Erina;Kitagawa, Osamu
在由外消旋轴手性3-（邻卤苯基）-2-甲基喹唑啉-4-酮衍生物制备的晶体中，分子间卤素键（C。O. X = Cl，Br，I），而在由它们的光学纯形式制备的晶体中，没有检测到这种卤素键合。
In the crystals prepared from racemic axially chiral 3-(orthohalophenyl)-2-methylquinazolin-4-one derivatives, the formation of intermolecular halogen bonding (C. O. X) between the carbonyl oxygen and ortho-halogen atom (X = Cl, Br, I) was found, while in the crystals prepared from their optically pure forms, such halogen bonding was not detected.