Daily mortality and particulate matter in different size classes in Erfurt, Germany
Daily mortality and particulate matter in different size classes in Erfurt, Germany
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DOI：
10.1038/sj.jes.7500538
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发表时间：
2007-08-01
影响因子：
4.5
通讯作者：
Peters, Annette
中科院分区：
文献类型：
--
作者：
Stoelzel, Matthias;Breitner, Susanne;Peters, Annette
许多研究已经调查了环境颗粒物（PM）浓度升高与死亡率增加之间的联系。在这里，我们分析了1995年至2001年之间，德国埃尔富特不同粒径组分对总死亡率和心肺死亡率的作用。数浓度（NC）的PM进行了测量，使用气溶胶光谱仪组成的微分迁移率粒度仪和激光气溶胶光谱仪，以表征颗粒之间的0.01和0.5之间和0.1和2.5 μ m，分别。我们推导了超微粒子NC的日平均值。ne（0.01-0.1 μ m）和for. ne颗粒（0.01-2.5 μ m）。假设一个恒定密度的球形颗粒，我们估计在这些尺寸范围内的颗粒的质量浓度（MC）。同时，从当地卫生部门获得每日总死亡和心肺死亡计数数据。使用Poisson广义加性模型分析数据，该模型使用平滑函数或指标变量调整趋势、季节性、流感流行、一周中的日期和气象。我们发现，在统计学上，高血糖与高血糖之间存在显著相关。ne颗粒（UFP;直径：0.01-0.1 μ m）NC和总死亡率以及心肺死亡率，各有4天滞后。UFP NC增加9748 cm（-3）的相对死亡风险（RR）为RR = 1.029，总死亡率的95%置信区间（CI）为1.003-1.055。对于心肺死亡率，我们发现：RR 1.031，95% CI：1.003-1.060。之间没有关联。结果表明，代表新鲜燃烧颗粒物的UFP可能是城市空气污染中与健康相关的重要组成部分。
The link between elevated concentrations of ambient particulate matter (PM) and increased mortality has been investigated in numerous studies. Here we analyzed the role of different particle size fractions with respect to total and cardio-respiratory mortality in Erfurt, Germany, between 1995 and 2001. Number concentrations (NC) of PM were measured using an aerosol spectrometer consisting of a Differential Mobility Particle Sizer and a Laser Aerosol Spectrometer to characterize particles between 0.01 and 0.5 and between 0.1 and 2.5 mu m, respectively. We derived daily means of particle NC for ultra. ne (0.01-0.1 mu m) and for. ne particles (0.01-2.5 mu m). Assuming spherical particles of a constant density, we estimated the mass concentrations (MC) of particles in these size ranges. Concurrently, data on daily total and cardio-respiratory death counts were obtained from local health authorities. The data were analyzed using Poisson Generalized Additive Models adjusting for trend, seasonality, influenza epidemics, day of the week, and meteorology using smooth functions or indicator variables. We found statistically significant associations between elevated ultra. ne particle (UFP; diameter: 0.01-0.1 mu m) NC and total as well as cardio-respiratory mortality, each with a 4 days lag. The relative mortality risk (RR) for a 9748 cm(-3) increase in UFP NC was RR = 1.029 and its 95% confidence interval (CI) 1.003-1.055 for total mortality. For cardio-respiratory mortality we found: RR 1.031, 95% CI: 1.003-1.060. No association between. ne particle MC and mortality was found.This study shows that UFP, representing fresh combustion particles, may be an important component of urban air pollution associated with health effects.