ALPHA-GANGLION AND DELTA-GANGLION CELLS IN THE RAT RETINA
ALPHA-GANGLION AND DELTA-GANGLION CELLS IN THE RAT RETINA
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DOI：
10.1002/cne.902860108
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发表时间：
1989-08-01
影响因子：
2.5
通讯作者：
PEICHL, L
中科院分区：
文献类型：
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作者：
PEICHL, L
在大鼠视网膜中，通过荧光黄和还原银染色的细胞内染色证明了一种独特的大神经节细胞。它们被称为α细胞，因为它们类似于其他哺乳动物视网膜的α细胞。还描述了第二类，称为增量电池。这两类都属于 Perry 定义的 I 型组（Proc. R. Soc. Lond. [Biol.] 204:363-375, ''79）。这两类树突树在内丛状层的内层或外层中分层，这可能对应于对光响应的开/关二分法。大鼠α细胞占所有神经节细胞的2-4%，其密度、大小和详细形态外观随视网膜位置而变化。与其他哺乳动物相比，大鼠的内部和外部分层α细胞显示出显着差异。在视网膜中央（在大细胞密度最大时），内部和外部α细胞的密度和树突状区域大小大致相等。然而，在视网膜周边，外部α细胞的数量最多是内部α细胞的三倍，并且树突区域的大小仅为内部α细胞的三分之一。最大密度约为110个α细胞/mm2；周边密度约为30个/mm2。最小的中心枝晶场直径为220μm。外部α细胞的外围树突域直径为350-550μm，内部α细胞的外围树突域直径为570-790μm。每个亚群分布在规则的马赛克中，树突域的区域排列提供了视网膜的均匀覆盖。无论其他数量差异如何，每个亚群的树突覆盖率都是 3 到 3.6 倍。根据形态数据预测α细胞的偏心率依赖性感受野大小。
In the rat retina a distinctive class of large ganglion cell was demonstrated by intracellular staining with Lucifer Yellow and with reduced silver staining. They are reffered to as alpha cell because they resemble the alpha cells of other mammalian retinae. A second class, called delta cells, is also described. Both classes belong to the type I group defined by Perry (Proc. R. Soc. Lond. [Biol.] 204:363-375, ''79). The dendritic trees of both classes stratify in either an inner or outer lamina of the inner plexiform layer which presumably corresponds to an on/off dichotomy in the response to light. Rat alpha cells constitute 2-4% of all ganglion cells, and their density, size, and detailed morphological appearance change with retinal location. Inner and outer stratifying alpha cells of the rat show significant differences compared to those of other mammals. In central retina (at the large cell density maximum) the densities and dendritic field sizes of inner and outer alpha cells are approximately equal. However, in peripheral retina outer alpha cells are up to three times more numerous and have dendritic field areas only one-third the size of those of the inner alpha cells. The maximal density is about 110 alpha cells/mm2; peripheral densities are about 30/mm2. The smallest central dendritic field diameters are 220 .mu.m. Peripheral dendritic field diameters are 350-550 .mu.m for outer and 570-790 .mu.m for inner alpha cells. Each subpopulation is distributed in a regular mosaic, and the territorial arrangement of the dendritic fields provides a homogeneous coverage of the retina. The dendritic coverage is three- to 3.6-fold for each subpopulation, irrespective of their other quantitative differences. Eccentricity-dependent receptive field sizes of the alpha cells are predicted from the morphological data.