Complex Coacervation: Chemically Stable Fibers Electrospun from Aqueous Polyelectrolyte Solutions
Complex Coacervation: Chemically Stable Fibers Electrospun from Aqueous Polyelectrolyte Solutions
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DOI：
10.1021/acsmacrolett.7b00173
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发表时间：
2017-05-01
影响因子：
7.015
通讯作者：
Schiffman, Jessica D.
中科院分区：
文献类型：
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作者：
Meng, Xiangxi;Perry, Sarah L.;Schiffman, Jessica D.
在这项研究中，我们首次证明水性复合凝聚层可以电纺成化学坚固的聚电解质复合物（PEC）纤维垫。 PEC 是由于带相反电荷的聚合物之间的静电络合而形成的。在这里，我们利用盐塑化 PEC 的能力，从而实现固体纤维的静电纺丝。静电纺丝溶液由一对强聚电解质、聚（4-苯乙烯磺酸钠盐）和聚（二烯丙基二甲基氯化铵）组成，使用溴化钾作为增塑盐。我们系统地研究了盐浓度和静电纺丝设备参数对纤维形成的影响。电纺 PEC 纤维垫在广泛的 pH 值、离子强度条件和许多有机溶剂下都很稳定。这项研究表明，水性复合凝聚层的静电纺丝可以生成化学稳定性强的独立式 PEC 纤维垫，同时避免对有机溶剂的依赖、在溶液中使用缠结的聚电解质的挑战以及对初纺纤维进行化学交联的需要。这些 PEC 纤维垫在必须使用环保纤维垫的应用中具有潜力，例如组织工程支架和水净化技术。
In this study, we provide the first demonstration that aqueous complex coacervates can be electrospun into chemically robust polyelectrolyte complex (PEC) fiber mats. PECs form due to electrostatic complexation between oppositely charged polymers. Here, we exploit the ability of salt to plasticize PECs, thus enabling the electrospinning of solid fibers. Electrospinning solutions were composed of a pair of strong polyelectrolytes, poly(4-styrenesulfonic acid, sodium salt) and poly(diallyldimethylammonium chloride) using potassium bromide as the plasticizing salt. We systematically investigated the effect of salt concentration and electrospinning apparatus parameters on fiber formation. Electrospun PEC fiber mats were stable over a wide range of pH values, ionic strength conditions, and many organic solvents. This study demonstrates that the electrospinning of aqueous complex coacervates can generate chemically robust, free-standing PEC fiber mats while circumventing the reliance on organic solvents, the challenge of working with entangled polyelectrolytes in solution, and the need to chemically cross-link the as-spun fibers. These PEC fiber mats hold potential in applications where environmentally benign fiber mats are imperative, such as tissue engineering scaffolds and water purification technologies.