Cortical areas supporting category learning identified using functional MRI
Cortical areas supporting category learning identified using functional MRI
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DOI：
10.1073/pnas.95.2.747
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发表时间：
1998-01-20
影响因子：
11.1
通讯作者：
Squire, LR
中科院分区：
文献类型：
--
作者：
Reber, PJ;Stark, CEL;Squire, LR
功能磁共振成像被用来确定参与类别学习的原型抽象的皮层区域。参与者研究了40个点模式，这些点模式是潜在原型的扭曲，然后在收集功能性MRI数据的同时，对新的点模式做出是或否的类别判断。点图案在主要需要“是”响应的点图案和主要需要“否”响应的点图案之间交替。活动在四个皮质区相关的类别判断任务A相当大的后枕叶皮质区（BA 17/18）表现出显着减少活动过程中的分类模式比在处理非分类模式。在处理分类模式的过程中，观察到左、右前额叶皮层（BA 10）和右下外侧额叶皮层（BA 44/47）的活动显着增加。当分类模式被评估时，视觉皮层的激活减少，这表明这些模式可以在原型被学习后以更快或更不费力的方式被处理。与处理分类模式相关的前额叶活动的增加可能与检索有关学习样本的信息的几个过程中的任何一个有关。
Functional MRI was used to identify cortical areas involved in category learning by prototype abstraction. Participants studied 40 dot patterns that were distortions of an underlying prototype and then, while functional MRI data were collected, made yes-no category judgments about new dot patterns. The dot patterns alternated between ones mostly requiring a "yes" response and ones mostly requiring a "no" response. Activity in four cortical areas correlated with the category judgment task A sizeable posterior occipital cortical area (BA 17/18) exhibited significantly less activity during processing of the categorical patterns than during processing of noncategorical patterns. Significant increases in activity during processing the categorical patterns were observed in left and right anterior frontal cortex (BA 10) and right inferior lateral frontal cortex (BA 44/47). Decreases in activation of visual cortex when categorical patterns were being evaluated suggest that these patterns could be processed in a more rapid or less effortful manner after the prototype had been learned. Increases in prefrontal activity associated with processing categorical patterns could be related to any of several processes involved in retrieving information about the learned exemplars.