A neural correlate of oculomotor sequences in supplementary eye field
A neural correlate of oculomotor sequences in supplementary eye field
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DOI：
10.1016/s0896-6273(02)00657-8
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发表时间：
2002-04-11
期刊：
影响因子：
16.2
通讯作者：
Hikosaka, O
中科院分区：
文献类型：
--
作者：
Lu, XF;Matsuzawa, M;Hikosaka, O
复杂的习得动作序列可以由少量基本动作的组合组成。为了研究大脑是如何呈现这些序列的，我们设计了一个视觉序列任务，在这个任务中，猴子必须完全根据序列背景来选择目标，而不是根据当前的刺激组合。我们发现，许多神经元在辅助眼场（SEF）成为活跃的特定目标方向（D神经元）或特定的目标/分心物组合（C神经元）。此外，这种活动通常是选择性的几个序列中的一个，包括组合（S神经元）。这些结果表明，SEF有助于在许多学习序列中产生扫视。
Complex learned motor sequences can be composed of a combination of a small number of elementary actions. To investigate how the brain represents such sequences, we devised an oculomotor sequence task in which the monkey had to choose the target solely by the sequential context, not by the current stimulus combination. We found that many neurons in the supplementary eye field (SEF) became active with a specific target direction (D neuron) or a specific target/distractor combination (C neuron). Furthermore, such activity was often selective for one among several sequences that included the combination (S neuron). These results suggest that the SEF contributes to the generation of saccades in many learned sequences.