Incidence of pulmonary tuberculosis among diabetics
Incidence of pulmonary tuberculosis among diabetics
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DOI：
10.1016/0962-8479(95)90529-4
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发表时间：
1995-12-01
期刊：
影响因子：
--
通讯作者：
Lee, EG
中科院分区：
文献类型：
--
作者：
Kim, SJ;Hong, YP;Lee, EG
设定：基于韩国糖尿病和非糖尿病公务员的纵向流行病学研究。目的：确定糖尿病和非糖尿病受试者之间肺结核（PTB）的比较发病率。设计：1988 ~ 1990年糖尿病与非糖尿病患者新发PTB的调查，根据每两年一次的体检和那些申请结核病健康保险的人的医疗记录。1990年对健康保险索赔人的医疗检查和医疗记录的调查显示，170名病人患上了肺结核（包括37例涂片阳性和8例培养阳性），806698例对照组中4935例（其中涂片阳性538例，培养阳性342例）。在糖尿病患者中，（1）所有类型，（2）涂片和/或培养阳性与（3）涂片阳性病例的PTB估计年发病率分别为1061、281和231/10（5），在非糖尿病对照组中分别为306、55和33/10（5）。7695例男性糖尿病患者中有167例发生PTB，320例女性糖尿病患者中有3例发生PTB，年龄越大糖尿病患者越多。糖尿病患者发生各种类型PTB和细菌学确诊病例的相对危险度（RR）分别是对照组的3.47倍和5.15倍，30-49岁组的RR高于50岁及以上组。
Setting: Longitudinal epidemiological study based on diabetic and non-diabetic civil servants in Korea.Objective: To determine a comparative incidence of pulmonary tuberculosis (PTB) between diabetic and non-diabetic subjects.Design: Investigation of newly developed PTB among diabetics and non-diabetics between 1988 and 1990, on the basis of biennial medical examination and the medical records of those who claimed health insurance for tuberculosis.Results: The 1990 medical examination and investigation of medical records of the health insurance claimants revealed that PTB had developed in 170 patients (including 37 smear and eight culture positives) among 8015 diabetics, and in 4935 patients (including 538 smear and 342 culture positives) among 806 698 control subjects. Estimated annual incidence rates of PTB of (1) all types, (2) smear and/or culture positive versus (3) smear positive cases were 1061, 281 and 231 per 10(5) respectively among diabetics and 306, 55 and 33 per 10(5) among non-diabetic controls. PTB developed in 167 of 7695 male diabetics and in 3 of 320 female diabetics, The greater the age, the more diabetics were found.Conclusion: Relative risks (RR) of developing PTB of all types and bacteriologically confirmed cases were 3.47 times and 5.15 times higher in the diabetics than in the matched controls, A greater RR was observed in those at the age of 30-49 than in those of 50 years or more.