Removal of oxytetracycline (OTC) in a synthetic pharmaceutical wastewater by sequential anaerobic multichamber bed reactor (AMCBR)/completely stirred tank reactor (CSTR) system: biodegradation and inhibition kinetics
Removal of oxytetracycline (OTC) in a synthetic pharmaceutical wastewater by sequential anaerobic multichamber bed reactor (AMCBR)/completely stirred tank reactor (CSTR) system: biodegradation and inhibition kinetics
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DOI：
10.1002/jctb.3706
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发表时间：
2012-07
影响因子：
3.4
通讯作者：
D. Sponza;H. Çelebi
中科院分区：
文献类型：
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作者：
D. Sponza;H. Çelebi
背景技术背景：传统的厌氧、好氧生物处理装置不能有效去除工业废水和市政废水中的抗生素。土霉素（OTC）对产甲烷菌和总挥发性脂肪酸（TVFA）的生物降解和抑制动力学研究较少。研究结果：高速率厌氧多室床反应器（AMCBR）在去除糖蜜化学需氧量（COD）和OTC抗生素方面是有效的，在进水OTC负荷率为133.33 gOTC m-3 day-1和水力停留时间（HRT）为2.25 d时，产率高达96%。将OTC负荷率从22.22 gOTC m−3 day−1增加到133.33 gOTC m−3 day−1，改善了糖蜜-COD的水解和比利用率。当OTC负荷> 133.33 gOTC m−3 day−1时，TVFA（KI−TVFA− methe）和OTC（KI−OTC− methe）对产甲烷菌的抑制常数降低。使用Halcobacterium抑制动力学评价了OTC负荷> 133.3 gOTC m−3 day−1对产酸菌和产甲烷菌的直接影响。结论：序贯AMCBR/CSTR工艺能有效去除非处方抗生素。在高OTC负荷下，Halcadine抑制常数（KID）显著降低，表明毒性增加。版权所有© 2012化学工业协会
BACKGROUND: The antibiotics in industrial and munipical wastewaters could not be removed effectively in conventional anaerobic and aerobic biological treatment plants. Few studies have been performed to investigate the biodegradation and inhibition kinetics of oxytetracycline (OTC) on methanogens and total volatile fatty acids (TVFA). RESULTS: A high rate anaerobic multichamber bed reactor (AMCBR) was effective in removing the molasses-chemical oxygen demand (COD), and the OTC antibiotic with yields as high as 96% at an influent OTC loading rate of 133.33 gOTC m−3 day−1 at a hydraulic retention time (HRT) of 2.25 days. Increasing the OTC loading rates from 22.22 gOTC m−3 day−1 to 133.33 gOTC m−3 day−1 improved both hydrolysis and specific utilization of molasses-COD. The inhibition constants of TVFA (KI−TVFA−meth) and OTC (KI−OTC−meth) on methanogens decreased at OTC loadings > 133.33 gOTC m−3 day−1. The direct effect of OTC loadings > 133.3 gOTC m−3 day−1 on acidogens and methanogens was evaluated using the Haldane inhibition kinetic. CONCLUSION: OTC antibiotic was effectively removed in a sequential AMCBR/completely stirred tank reactor (CSTR). The Haldane inhibition constant (KID) decreased significantly at high OTC loads indicating the increase in toxicity. Copyright © 2012 Society of Chemical Industry