LYCORINE ALKALOIDS FROM HYMENOCALLIS-LITTORALIS
LYCORINE ALKALOIDS FROM HYMENOCALLIS-LITTORALIS
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DOI：
10.1016/0031-9422(95)00372-e
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发表时间：
1995-11-01
期刊：
影响因子：
3.8
通讯作者：
RUANGRUNGSI, N
中科院分区：
文献类型：
--
作者：
LIN, LZ;HU, SF;RUANGRUNGSI, N
从小膜壳中分离得到一个新的生物碱，命名为Littoraline，以及13个已知的石蒜碱和1个木脂素。用一维和二维核磁共振技术确定了该新生物碱的结构和核磁共振归属。Littoraline具有抑制HIV逆转录酶的活性，而Lycorine和Haemanthamine具有较强的体外细胞毒性。
From Hymenocallis littoralis, one new alkaloid, named littoraline, together with 13 known lycorine alkaloids and one lignan, were isolated. The structure and NMR assignments of this new alkaloid were determined by 1D and 2D NMR techniques. Littoraline showed inhibitory activity of HIV reverse transcriptase, and lycorine and haemanthamine showed potent in vitro cytotoxicity.