2D- und 3D-Parameterbilder zur Analyse der Kontrastmittelverteilung bei dynamischen CT- und MR-Untersuchungen

2D- und 3D-Parameterbilder zur Analyse der Kontrastmittelverteilung bei dynamischen CT- und MR-Untersuchungen
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动态 CT 和 MR 下的控制分析的 2D 和 3D 参数图像

DOI:
10.1007/s001170050431
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发表时间:
1998
期刊:
Der Radiologe
影响因子:
--
通讯作者:
R. Felix
R. Felix
中科院分区:
--
文献类型:
--
作者:
J. Beier;T. Büge;C. Stroszczynski;H. Oellinger;E. Fleck;R. Felix

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对于动态对比介质(CM)研究,参数图像利用每个像素的时间/强度曲线(TIC)的特定特征,并在新图像中表示这些值。二维CM分析的现有概念扩展到三维应用,使用适当的计算机图形可视化。方法影像学:CM静脉注射;利用快速CT采集单片进行第一次分析;40张MR切片累积CM(每90秒6序列= 240张图像):软件:任意2D/3D区域的TIC;参数图:(1)所有体素随时间的时间最大强度投影(tip),(2)基于TIC幅值的时间CM梯度(TG),(3) TIC斜率,(4)TIC峰值时间,(5)与参考TIC的相关系数。利用多平面重构、MIP、表面重构、体绘制、纹理映射和动画等方法对CM积累计算的三维数据进行可视化。结果在第一次分析中,TMIP和TG可以同时或分开显示CM丸的不同时间阶段。相关图像强调与给定TIC模式相似的区域。三维计算机图形技术实现了(1)原始图像和CM积累的解剖/功能映射;(2)融合显示空间CM增强和TIC峰值的颜色编码时间。结论对局部图像区域CM积累的存在、大小和峰值时间的量化支持对血管化和缺血或坏死区域的评估。
AimFor dynamic contrast medium (CM) studies, parameter images exploit specific features of the time/intensity curve (TIC) of each pixel and represent these values in a new image. Existing concepts of two-dimensional CM analysis are extended for three-dimensional applications using adequate computer graphic visualization.MethodsImaging: intravenous CM injection; first-pass analysis using fast CT acquisition of a single slice; CM accumulation by 40 MR slices (6 sequences every 90 s= 240 images): Software: TIC of arbitrary 2D/3D regions; parameter images:(1) temporal maximum intensity projection (TMIP) of all voxels over time,(2) temporal CM gradients (TG) based on TIC amplitude,(3) TIC slope,(4) time of TIC peak,(5) correlation coefficient to reference TIC. The calculated 3D data of CM accumulation was visualized using multiplanar reformation, MIP, surface reconstruction, volume rendering, texture mapping and animation.ResultsIn first-pass analyses, TMIP and TG allowed the simultaneous or separated presentation of different temporal phases of the CM bolus. Correlation images emphasized regions with similarities to given TIC patterns. Three-dimensional computer graphic techniques enabled (1) anatomical/functional mapping of original image and CM accumulation and (2) fused display of both spatial CM enhancement and color-encoded time of TIC peak in one common image.ConclusionsThe quantification of presence, magnitude, and time-of-peak of CM accumulation in local image regions supports the assessment of vascularization and of ischemic or necrotic areas.