History of the enzyme nomenclature system
History of the enzyme nomenclature system
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DOI：
10.1093/bioinformatics/16.1.34
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发表时间：
2000-01-01
期刊：
影响因子：
5.8
通讯作者：
Boyce, S
中科院分区：
文献类型：
--
作者：
Tipton, K;Boyce, S
命名事物对于人们相互理解至关重要，无论涉及什么语言或兴趣领域。酶、基因和化学物质都是如此，鸟类、食物、花朵等也是如此。有效的沟通需要避免歧义，但在实践中，即使在世界不同地区，甚至在同一个国家使用同一种语言的人们之间，歧义也很多。然而，对于普通物体或动作的含糊不清的词汇已经成为许多或多或少令人难忘的笑话的基础，它们也会造成很大的混乱。这种语言上的混乱受到许多人的欢迎，因为它是多元文化遗产的一部分，应该不惜一切代价加以保护，以防止我们陷入奥威尔式的“新话”。然而;在科学领域，如果别人能够理解你在做什么，那就有明显的优势。许多团体强调在化学、遗传学、酶学等领域需要标准化的、普遍接受的命名系统。然而;通常是普遍的接受导致了这个问题。很少有人会承认他们发现命名法是一门有趣的学科，但如果有人建议为了清晰或统一而改变他们所喜爱的命名法，许多自称蔑视命名法的人会非常兴奋。本文将讨论酶命名系统的发展、优点、缺点和未来展望。联系:ktipton@tcd.ie。
Naming things is essential for people To understand one another no matter what language or field of interest is involved. This is as true for enzymes, genes and chemicals as it is for birds, food, flowers, etc. Effective communication requires a lack of ambiguity, but, in practice, ambiguities abound even, between people who use the same language in different parts of the world, or even within the same country. Whereas ambiguities in the words used for common objects or actions have been the basis for many, more-or-less memorable jokes, they can also cause a great deal of confusion. Such linguistic chaos is welcomed by many as being a part of a diverse heritage that should be preserved at all costs to prevent us from descending into Orwellian 'newspeak'. However; in the sciences, ther-e are distinct advantages in others being able to understand what one is doing. Many groups have stressed the need for standardized, universally accepted systems of nomenclature in chemistry, genetics, enzymology, etc. However; it is the universal acceptance that usually causes the problem. It is rare to find people who will admit that they find nomenclature to be an interesting subject but many who profess contempt for it will get very excited if it is suggested that their pet nomenclature should be changed in the interest of clarity or uniformity. This account will consider the development of the enzyme nomenclature system, its benefits, shortcomings and future prospects. Contact: ktipton@tcd.ie.