Genetic influences on suicide and nonfatal suicidal behavior: twin study findings.
Genetic influences on suicide and nonfatal suicidal behavior: twin study findings.
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遗传对自杀和非致命自杀行为的影响：双胞胎研究结果。
DOI：
10.1016/j.eurpsy.2009.12.008
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发表时间：
2010-06
期刊：
影响因子：
--
通讯作者：
Fiske A
中科院分区：
文献类型：
--
作者：
Pedersen NL;Fiske A
自杀行为是家族性的，这一点已经得到了充分的证实。双胞胎研究提供了一个独特的机会来区分遗传影响和其他家族影响。瑞典双胞胎登记处的数据与之前双胞胎研究的结果一致，包括病例系列和选定的样本，数据清楚地表明了基因对自杀的影响的重要性。对自杀意念和自杀企图的双胞胎研究也涉及到遗传影响，即使考虑到了精神病理学的影响。未来的工作需要评估年龄和性别差异在自杀和非致命性自杀行为遗传性方面的可能性。
It has been well established that suicidal behavior is familial. Twin studies provide a unique opportunity to distinguish genetic effects from other familial influences. Consistent with findings from previous twin studies, including case series and selected samples, data from the population-based Swedish Twin Registry clearly demonstrate the importance of genetic influences on suicide. Twin studies of suicidal ideation and suicide attempts also implicate genetic influences, even when accounting for the effects of psychopathology. Future work is needed to evaluate the possibility of age and gender differences in heritability of suicide and nonfatal suicidal behavior.