Benzoyl trifluoromethanesulfonate. A mild reagent for the benzoylation of sterically hindered hydroxyls
Benzoyl trifluoromethanesulfonate. A mild reagent for the benzoylation of sterically hindered hydroxyls
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三氟甲磺酸苯甲酰酯。
DOI：
10.1021/jo00195a001
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发表时间：
1984
影响因子：
3.6
通讯作者：
M. Koreeda*
中科院分区：
文献类型：
--
作者：
L. Brown;M. Koreeda*
三氟甲磺酸苯甲酰酯 (BzOTf) 是一种高效试剂，可在温和条件下对多种醇进行苯甲酰化。这些包括受阻仲羟基和叔羟基、酚和α-二醇。当反应在吡啶存在下进行时，敏感官能团是稳定的。路易斯酸敏感化合物的几种独特的重排也受到影响。
Benzoyl trifluoromethanesulfonate (BzOTf) is a highly efficient reagent for the benzoylation of a variety of alcohols under mild conditions. These include hindered secondary and tertiary hydroxyls, phenols, and a-glycols. Sensitive functionality is stable when the reaction is performed in the presence of pyridine. Several unique rearrangements of Lewisacid sensitive compounds were also effected.